2. Gene
  3. PLEKHG1 - pleckstrin homology and RhoGEF domain containing G1 Gene

PLEKHG1 - pleckstrin homology and RhoGEF domain containing G1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 pleckstrin 同源性和 RhoGEF 结构域 G1

种属: Homo sapiens

同用名: ARHGEF41

基因 ID: 57480 | 基因类型: protein coding

关于 PLEKHG1

This gene has 9 transcripts (splice variants), 210 orthologues and 22 paralogues. Broad expression in spleen (RPKM 8.2), lymph node (RPKM 3.6) and 21 other tissues.

功能概要

预测可启用胍基核苷酸交换因子活性。预测参与调节小 GTPase 介导的信号转导。位于核质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of small GTPase mediated signal transduction. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

PLEKHG1 基因产物(10)

mRNA Protein Name
NM_001029884.3 NP_001025055.1 pleckstrin homology domain-containing family G member 1 isoform c
NM_001329798.2 NP_001316727.1 pleckstrin homology domain-containing family G member 1 isoform a
NM_001329799.2 NP_001316728.1 pleckstrin homology domain-containing family G member 1 isoform b
NM_001329800.2 NP_001316729.1 pleckstrin homology domain-containing family G member 1 isoform c
NM_001329801.2 NP_001316730.1 pleckstrin homology domain-containing family G member 1 isoform c
NM_001329802.2 NP_001316731.1 pleckstrin homology domain-containing family G member 1 isoform d
NM_001329803.2 NP_001316732.1 pleckstrin homology domain-containing family G member 1 isoform e
NM_001329804.2 NP_001316733.1 pleckstrin homology domain-containing family G member 1 isoform f
NM_001329805.2 NP_001316734.1 pleckstrin homology domain-containing family G member 1 isoform f
NM_001329806.2 NP_001316735.1 pleckstrin homology domain-containing family G member 1 isoform f

PLEKHG1 蛋白结构

RhoGEF

RhoGEF: RhoGEF domain (117 - 292)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1385 a.a.
蛋白主名 其他名称

pleckstrin homology domain-containing family G member 1

pleckstrin homology domain containing, family G (with RhoGef domain) member 1

关联疾病

疾病名称 别名
Panic Disorder

Panic Anxiety Syndrome

Panic

Panic Disorder 1

Episodic Paroxysmal Anxiety Disorder
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10689 PLEKHG1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta PLEKHG1 VGNC VGNC:83445
Mus musculus PLEKHG1 MGD MGI:2676551
Felis catus PLEKHG1 VGNC VGNC:64226
Rattus norvegicus PLEKHG1 RGD RGD:1583676
Canis familiaris PLEKHG1 VGNC VGNC:44676
Bos taurus PLEKHG1 VGNC VGNC:33014
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