2. Gene
  3. IGSF9 - immunoglobulin superfamily member 9 Gene

IGSF9 - immunoglobulin superfamily member 9 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：免疫球蛋白超家族成员 9

种属: Homo sapiens

同用名: Nrt1; IGSF9A; FP18798

基因 ID: 57549 | 基因类型: protein coding

关于 IGSF9

Cytogenetic location: 1q23.2 Genomic coordinates (GRCh38): 1:159,927,041-159,945,613 (from NCBI)

This gene has 5 transcripts (splice variants), 121 orthologues and 36 paralogues. Biased expression in skin (RPKM 12.2), stomach (RPKM 7.5) and 8 other tissues.

功能概要

预测可启用细胞间粘附介体活性。预计参与轴突导向；树突自我回避；和通过质膜粘附分子的嗜同细胞粘附。预计在突触组织的树突发育和调节的上游或内部起作用。预测位于树突和抑制性突触中。预计是膜的组成部分。预计在轴突和质膜中有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable cell-cell adhesion mediator activity. Predicted to be involved in axon guidance; dendrite self-avoidance; and homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to act upstream of or within dendrite development and regulation of synapse organization. Predicted to be located in dendrite and inhibitory synapse. Predicted to be integral component of membrane. Predicted to be active in axon and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

IGSF9 基因产物(2)

mRNA Protein Name
NM_001135050.2 NP_001128522.1 protein turtle homolog A isoform a precursor
NM_020789.4 NP_065840.2 protein turtle homolog A isoform b precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

IGSF9 蛋白结构

I-set

I-set: Immunoglobulin I-set domain (136 - 223)

Ig_2

Ig_2: Immunoglobulin domain (227 - 319)

Ig_2

Ig_2: Immunoglobulin domain (329 - 402)

I-set

I-set: Immunoglobulin I-set domain (426 - 502)

fn3

fn3: Fibronectin type III domain (512 - 596)

fn3

fn3: Fibronectin type III domain (625 - 707)

  • 0
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  • 1179 a.a.
蛋白主名 其他名称

protein turtle homolog A

immunoglobulin superfamily member 9A

关联疾病

疾病名称 别名
Ovarian Endometrioid Stromal Sarcoma
Ovary Sarcoma

Sarcoma Of Ovary
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06652 IGSF9 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS06653 IGSF9B Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS20961 Igsf9 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS27478 Igsf9 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris IGSF9 VGNC VGNC:41919
Rattus norvegicus IGSF9 RGD RGD:1304566
Bos taurus IGSF9 VGNC VGNC:30097
Mus musculus IGSF9 MGD MGI:2135283
Macaca mulatta IGSF9 VGNC VGNC:73620
Felis catus IGSF9 VGNC VGNC:97462
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