2. Gene
  3. Ltbp1 - latent transforming growth factor beta binding protein 1 Gene

Ltbp1 - latent transforming growth factor beta binding protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 59107 | 基因类型: protein coding

关于 Ltbp1

功能概要

Predicted to enable microfibril binding activity and transforming growth factor beta binding activity. Involved in several processes, including cellular response to mechanical stimulus; cellular response to parathyroid hormone stimulus; and cellular response to platelet-derived growth factor stimulus. Located in several cellular components, including dendrite; neuronal cell body; and perinuclear region of cytoplasm. Part of large latent transforming growth factor-beta complex. Biomarker of glomerulonephritis and transient cerebral ischemia. Human ortholog(s) of this gene implicated in cutis laxa. Orthologous to human LTBP1 (latent transforming growth factor beta binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Ltbp1 基因产物(1)

mRNA Protein Name
NM_021587.2 NP_067598.2 latent-transforming growth factor beta-binding protein 1 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to mechanical stimulus IEP
IEP: 通过表达模式推断
9607192 RGD
involved in cellular response to parathyroid hormone stimulus IEP
IEP: 通过表达模式推断
15880704 RGD
involved in cellular response to platelet-derived growth factor stimulus IEP
IEP: 通过表达模式推断
14708940 RGD
involved in cellular response to vitamin D IEP
IEP: 通过表达模式推断
10025676 RGD
involved in positive regulation of collagen biosynthetic process IMP
IMP: 通过突变表型推断
9607192 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in collagen-containing extracellular matrix IDA
IDA: 通过直接分析推断
9766531 RGD
located in dendrite IDA
IDA: 通过直接分析推断
11720783 RGD
part of large latent transforming growth factor-beta complex IDA
IDA: 通过直接分析推断
11907708 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
11720783 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
9828223 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

latent-transforming growth factor beta-binding protein 1

LTBP-1

LanC (bacterial lantibiotic synthetase component C)-like 1

TGF-beta-1-BP-1

transforming growth factor beta-1-binding protein 1

transforming growth factor beta-1-masking protein large subunit

transforming growth factor-beta (TGF-beta) masking p

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07877 LTBP1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS20052 Ltbp1 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS26556 Ltbp1 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ltbp1 NCBI NCBI:4052
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