2. Gene
  3. Mark2 - microtubule affinity regulating kinase 2 Gene

Mark2 - microtubule affinity regulating kinase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 60328 | 基因类型: protein coding

关于 Mark2

功能概要

Enables protein N-terminus binding activity; protein kinase activity; and Tau Protein binding activity. Involved in several processes, including establishment or maintenance of cell polarity regulating cell shape; generation of neurons; and protein phosphorylation. Located in membrane. Orthologous to human MARK2 (microtubule affinity regulating kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Mark2 基因产物(2)

mRNA Protein Name
NM_001398633.1 NP_001385562.1 serine/threonine-protein kinase MARK2 isoform 2
NM_021699.3 NP_067731.1 serine/threonine-protein kinase MARK2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
14741102 RGD
enables protein serine/threonine kinase activity IDA
IDA: 通过直接分析推断
14741102 RGD
enables protein serine/threonine kinase activity IMP
IMP: 通过突变表型推断
9108484 RGD
enables tau protein binding IPI
IPI: 通过物理相互作用推断
24251416 RGD
enables tau-protein kinase activity IDA
IDA: 通过直接分析推断
14517247 RGD
enables tau-protein kinase activity IMP
IMP: 通过突变表型推断
24251416 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in axon development IMP
IMP: 通过突变表型推断
16717194 RGD
involved in establishment or maintenance of cell polarity regulating cell shape IMP
IMP: 通过突变表型推断
16717194 RGD
involved in neuron migration IDA
IDA: 通过直接分析推断
14741102 RGD
involved in peptidyl-serine phosphorylation IDA
IDA: 通过直接分析推断
10542369 RGD
involved in peptidyl-serine phosphorylation IMP
IMP: 通过突变表型推断
16717194 RGD
involved in protein autophosphorylation IDA
IDA: 通过直接分析推断
14517247 RGD
involved in protein phosphorylation IMP
IMP: 通过突变表型推断
9108484 RGD
involved in regulation of cytoskeleton organization IDA
IDA: 通过直接分析推断
14517247 RGD
involved in regulation of microtubule cytoskeleton organization IDA
IDA: 通过直接分析推断
10542369 RGD
involved in regulation of postsynapse organization IDA
IDA: 通过直接分析推断
22807451 RGD
involved in regulation of postsynapse organization IMP
IMP: 通过突变表型推断
22807451 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
22807451 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
22807451 RGD
located in membrane IDA
IDA: 通过直接分析推断
14741102 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

serine/threonine-protein kinase MARK2

ELKL motif kinase 1

EMK-1

EMK1

MAP/microtubule affinity-regulating kinase 2

serine/threonine kinase

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-120877 MRT199665 99.74% 否
HY-139604 PCC0208017 99.56% 否
HY-148062 RSS0680 99.85% 否
HY-120877A (R)-MRT199665 98.70% 否
HY-RS08150 MARK2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS17609 Mark2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS24069 Mark2 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mark2 NCBI NCBI:2011
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