2. Gene
  3. MARCKSL1 - MARCKS like 1 Gene

MARCKSL1 - MARCKS like 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：马克斯样 1

种属: Homo sapiens

同用名: F52; MLP; MRP; MLP1; MACMARCKS

基因 ID: 65108 | 基因类型: protein coding

关于 MARCKSL1

Cytogenetic location: 1p35.1 Genomic coordinates (GRCh38): 1:32,333,839-32,336,233 (from NCBI)

This gene has 1 transcript (splice variant), 124 orthologues and 1 paralogue. Broad expression in ovary (RPKM 132.8), brain (RPKM 127.5) and 24 other tissues.

功能概要

该基因编码豆蔻酰化富含丙氨酸的 C 激酶底物 (MARCKS) 家族的成员。该家族的成员在细胞骨架调节、蛋白激酶 C 信号和钙调蛋白信号中发挥作用。编码的蛋白质影响粘附连接的形成。可变剪接导致多个转录本变体。该基因的假基因位于 6 号和 10 号染色体的长臂上。[RefSeq 提供，2012 年 6 月]

This gene encodes a member of the myristoylated alanine-rich C-kinase substrate (MARCKS) family. Members of this family play a role in cytoskeletal regulation, protein kinase C signaling and Calmodulin signaling. The encoded protein affects the formation of adherens junction. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on the long arm of chromosomes 6 and 10. [provided by RefSeq, Jun 2012]

MARCKSL1 基因产物(1)

mRNA Protein Name
NM_023009.7 NP_075385.1 MARCKS-related protein
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
24863880 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MARCKSL1 蛋白结构

MARCKS

MARCKS: MARCKS family (4 - 59)

MARCKS

MARCKS: MARCKS family (57 - 186)

  • 0
  • 100
  • 195 a.a.
蛋白主名 其他名称

MARCKS-related protein

MARCKS-like protein 1

关联疾病

疾病名称 别名
Valproate Embryopathy

Fetal Valproate Syndrome

Fetal Valproic Acid Syndrome

Fvs

Valproic Acid Embryopathy

Fetal Valproate Spectrum Disorder

Valproate Embryopathy, Susceptibility To

Foetal Valproate Syndrome

Foetal Valproic Acid Syndrome

Susceptibility To Valproate Embryopathy

Valproic Acid Antenatal Infection
Neural Tube Defects

Spina Bifida

Neural Tube Defect

NTD

Neural Tube Defects, Susceptibility To

Spinal Dysraphism

Spina Bifida, Susceptibility To

Rachischisis

Cleft Spine

Open Spine

Hydrocele Spinalis

Neural Tube Defect Nos

Sb - [Spina Bifida]

Spinal Hernia Nos

Spinal Fissure Nos
Anencephaly

Aprosencephaly

Anencephalus

Congenital Absence Of Brain

Absence Of A Large Part Of The Brain And The Skull

Anencephalia

Anencephalic Monster

Brain Absence

Brain Agenesis

Brain Aplasia

Absent Brain

Anencephalic

Congenital Absence Of Cerebrum

Congenital Hemicrania

Incomplete Anencephaly
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08146 MARCKSL1 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus MARCKSL1 VGNC VGNC:31245
Canis familiaris MARCKSL1 VGNC VGNC:43022
Rattus norvegicus MARCKSL1 RGD RGD:621197
Macaca mulatta MARCKSL1 VGNC VGNC:74723
Felis catus MARCKSL1 VGNC VGNC:107582
Mus musculus MARCKSL1 MGD MGI:97143
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