2. Gene
  3. POLR3D - RNA polymerase III subunit D Gene

POLR3D - RNA polymerase III subunit D Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：RNA 聚合酶 III 亚基 D

种属: Homo sapiens

同用名: C53; RPC4; BN51T; RPC53; TSBN51

基因 ID: 661 | 基因类型: protein coding

关于 POLR3D

Cytogenetic location: 8p21.3 Genomic coordinates (GRCh38): 8:22,245,133-22,254,601 (from NCBI)

This gene has 5 transcripts (splice variants) and 200 orthologues. Ubiquitous expression in testis (RPKM 12.6), placenta (RPKM 8.6) and 25 other tissues.

功能概要

该基因补充了从 BHK-21 叙利亚仓鼠细胞系中分离出的温度敏感突变体。它会导致在非允许温度下细胞周期的 G1 期进展受阻。[RefSeq 提供，2008 年 7 月]

This gene complements a temperature-sensitive mutant isolated from the BHK-21 Syrian hamster cell line. It leads to a block in progression through the G1 phase of the cell cycle at nonpermissive temperatures. [provided by RefSeq, Jul 2008]

POLR3D 基因产物(1)

mRNA Protein Name
NM_001722.3 NP_001713.2 DNA-directed RNA polymerase III subunit RPC4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin binding IDA
IDA: 通过直接分析推断
24107381 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of innate immune response IDA
IDA: 通过直接分析推断
19631370 GOA
involved in positive regulation of interferon-beta production IDA
IDA: 通过直接分析推断
19631370 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of RNA polymerase III complex IDA
IDA: 通过直接分析推断
24107381 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

POLR3D 蛋白结构

RNA_pol_Rpc4

RNA_pol_Rpc4: RNA polymerase III RPC4 (263 - 389)

  • 0
  • 100
  • 200
  • 300
  • 398 a.a.
蛋白主名 其他名称

DNA-directed RNA polymerase III subunit RPC4

BN51 (BHK21) temperature sensitivity complementing

关联疾病

疾病名称 别名
Lipoid Congenital Adrenal Hyperplasia

Congenital Adrenal Hyperplasia

Congenital Lipoid Adrenal Hyperplasia Due To Star Deficency

Congenital Lipoid Adrenal Hyperplasia

Lipoid Cah

Lipoid Adrenal Hyperplasia

Adrenal Hyperplasia 1

Cah

Clah

LCAH

Adrenal Hyperplasia I

Lipoid Hyperplasia, Congenital, Of Adrenal Cortex With Male Pseudohermaphroditism

Congenital Adrenal Hyperplasia Lipoid

Adrenal Hyperplasia, Congenital

Congenital Adrenal Hyperplasia, Lipoid

AH1

Congenital Lipoid Hyperplasia Of Adrenal Cortex With Male Pseudohermaphroditism

Adrenal Hyperplasia Congenital

Hyperplasia, Adrenal, Lipoid, Congenital

Congenital Adrenogenital Disorders Associated With Enzyme Deficiency

Congenital Adrenal Cortical Hyperplasia

Congenital Adrenal Gland Hyperplasia

Congenital Adrenogenital Syndrome

Congenital Hyperadrenocorticism

Congenital Adrenogenitalism

Congenital Female Adrenal Pseudohermaphroditism
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10858 POLR3D Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta POLR3D VGNC VGNC:76017
Felis catus POLR3D VGNC VGNC:64292
Bos taurus POLR3D VGNC VGNC:33148
Mus musculus POLR3D MGD MGI:1914315
Canis familiaris POLR3D VGNC VGNC:44803
Rattus norvegicus POLR3D RGD RGD:1311816
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