2. Gene
  3. Casq1 - calsequestrin 1 Gene

Casq1 - calsequestrin 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 686019 | 基因类型: protein coding

关于 Casq1

功能概要

Enables calcium ion binding activity. Involved in several processes, including regulation of sequestering of calcium ion; response to denervation involved in regulation of muscle adaptation; and skeletal muscle tissue development. Located in I band; T-tubule; and terminal cisterna lumen. Colocalizes with Golgi apparatus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human CASQ1 (calsequestrin 1). [provided by Alliance of Genome Resources, Apr 2022]

Casq1 基因产物(1)

mRNA Protein Name
NM_001159594.1 NP_001153066.1 calsequestrin-1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium ion binding IDA
IDA: 通过直接分析推断
19029185 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of sequestering of calcium ion IDA
IDA: 通过直接分析推断
19029185 RGD
involved in response to denervation involved in regulation of muscle adaptation IEP
IEP: 通过表达模式推断
15138610 RGD
involved in response to muscle inactivity IEP
IEP: 通过表达模式推断
11546666 RGD
involved in skeletal muscle tissue development IEP
IEP: 通过表达模式推断
8600158 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in I band IDA
IDA: 通过直接分析推断
15684334 RGD
located in T-tubule IDA
IDA: 通过直接分析推断
11010809 RGD
located in myofibril IDA
IDA: 通过直接分析推断
15684334 RGD
located in sarcolemma IDA
IDA: 通过直接分析推断
15684334 RGD
located in sarcoplasmic reticulum IDA
IDA: 通过直接分析推断
19029185 RGD
located in terminal cisterna IDA
IDA: 通过直接分析推断
11010809 RGD
located in terminal cisterna lumen IDA
IDA: 通过直接分析推断
6355123 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

calsequestrin-1

Aspartactin

Laminin-binding protein

calsequestrin 1 (fast-twitch, skeletal muscle)

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01972 CASQ1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19990 Casq1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26494 Casq1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Casq1 NCBI NCBI:844
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