2. Gene
  3. Tpmt - thiopurine S-methyltransferase Gene

Tpmt - thiopurine S-methyltransferase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 690050 | 基因类型: protein coding

关于 Tpmt

功能概要

Predicted to enable S-adenosyl-L-methionine binding activity and thiopurine S-methyltransferase activity. Involved in response to testosterone. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; alopecia; leukopenia; and thiopurine S-methyltransferase deficiency. Orthologous to human TPMT (thiopurine S-methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Tpmt 基因产物(1)

mRNA Protein Name
NM_001395670.1 NP_001382599.1 thiopurine S-methyltransferase
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
3994729 RGD
involved in response to testosterone IEP
IEP: 通过表达模式推断
1897245 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

thiopurine S-methyltransferase

thiopurine methyltransferase

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14940 TPMT Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-134062 7-Methyl-6-mercaptopurine / 否
HY-RS18794 Tpmt Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25283 Tpmt Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tpmt NCBI NCBI:7172
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