2. Gene
  3. TGM4 - transglutaminase 4 Gene

TGM4 - transglutaminase 4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：转谷氨酰胺酶 4

种属: Homo sapiens

同用名: TGP; hTGP

基因 ID: 7047 | 基因类型: protein coding

关于 TGM4

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:44,874,608-44,914,990 (from NCBI)

This gene has 7 transcripts (splice variants), 1 gene allele, 72 orthologues and 8 paralogues. Restricted expression toward prostate (RPKM 891.0).

功能概要

预测启用蛋白质-谷氨酰胺γ-谷氨酰转移酶活性。预测参与肽交联。预计在交配插头结构的上游或内部起作用。位于高尔基体和含胶原蛋白的细胞外基质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable protein-glutamine gamma-glutamyltransferase activity. Predicted to be involved in peptide cross-linking. Predicted to act upstream of or within mating plug formation. Located in Golgi apparatus and collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022]

TGM4 基因产物(1)

mRNA Protein Name
NM_003241.4 NP_003232.2 protein-glutamine gamma-glutamyltransferase 4
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
20569004 GOA
located in collagen-containing extracellular matrix IDA
IDA: 通过直接分析推断
20596668 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
20596668 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TGM4 蛋白结构

Transglut_N

Transglut_N: Transglutaminase family (8 - 123)

Transglut_core

Transglut_core: Transglutaminase-like superfamily (253 - 351)

Transglut_C

Transglut_C: Transglutaminase family, C-terminal ig like domain (587 - 684)

  • 0
  • 200
  • 400
  • 600
  • 684 a.a.
蛋白主名 其他名称

protein-glutamine gamma-glutamyltransferase 4

TG(P)

关联疾病

疾病名称 别名
Essential Tremor

Benign Essential Tremor

Familial Tremor

Hereditary Essential Tremor

Essential Hereditary Tremor

Shaky Hand Syndrome

Benign Essential Tremor Syndrome

Tremor Hereditary Essential

Essential Tremor, Susceptibility To

Tremor, Hereditary Essential
Autoimmune Polyendocrine Syndrome Type 1

Whitaker Syndrome

Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy

Autoimmune Polyglandular Syndrome I

Polyglandular Type I Autoimmune Syndrome
Prostate Cancer

Prostate Carcinoma

Prostate Cancer, Familial

Prostate Neoplasm

Prostate Cancer, Somatic

Prostate Cancer, Susceptibility To

Prostatic Cancer

Prostatic Neoplasms

Hereditary Prostate Cancer

Prostatic Neoplasm

Cancer Of Prostate

Carcinoma Of Prostate

Familial Prostate Cancer

Familial Prostate Carcinoma

Malignant Tumor Of Prostate

Malignant Neoplasm Of Prostate

Prostate Cancer, Familial, Susceptibility To

Malignant Tumor Of The Prostate

Ngp - New Growth Of Prostate

Tumor Of The Prostate

Prostate Cancer, Hereditary

Cancer Of The Prostate

Malignant Neoplasm Of The Prostate

Prostatic Carcinoma

PC

Prca

Cancer, Prostate

Malignant Prostatic Tumour

Malignant Tumour Of Prostate

Primary Prostate Cancer

Primary Malignant Neoplasm Of Prostate

Prostate Gland Cancer
Pelvic Varices

Varix Of Pelvis

Pelvic Varicose Vein
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14461 TGM4 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus TGM4 RGD RGD:620785
Mus musculus TGM4 MGD MGI:3027002
Macaca mulatta TGM4 VGNC VGNC:110335
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