1. Gene
  2. Aifm2 - apoptosis-inducing factor, mitochondrion-associated 2 Gene

Aifm2 - apoptosis-inducing factor, mitochondrion-associated 2 Gene

种属: Mus musculus

同用名: Amid; FSP1; PRG3; 5430437E11Rik; D730001I10Rik

基因 ID: 71361 | 基因类型: protein coding

关于 Aifm2

功能概要

Predicted to enable several functions, including electron-transferring-flavoprotein dehydrogenase activity; flavin adenine dinucleotide binding activity; and oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor. Involved in regulation of cellular response to oxidative stress. Located in mitochondrial membrane and nucleus. Is expressed in adrenal medulla; central nervous system; and retina. Orthologous to human AIFM2 (Apoptosis inducing factor mitochondria associated 2). [provided by Alliance of Genome Resources, Apr 2022]

Aifm2 基因产物(4)

mRNA Protein Name
NM_001039194.3 NP_001034283.1 ferroptosis suppressor protein 1 isoform 2
NM_001284300.1 NP_001271229.1 ferroptosis suppressor protein 1 isoform 2
NM_153779.2 NP_722474.2 ferroptosis suppressor protein 1 isoform 1
NM_178058.4 NP_835159.1 ferroptosis suppressor protein 1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
26689472 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of cellular response to oxidative stress IMP
IMP: 通过突变表型推断
26689472 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
26689472 MGI
located in mitochondrial membrane IDA
IDA: 通过直接分析推断
26689472 MGI
located in nucleus IDA
IDA: 通过直接分析推断
26689472 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ferroptosis suppressor protein 1

apoptosis-inducing factor (AIF)-like mitochondrion-associated inducer of death

apoptosis-inducing factor 2

apoptosis-inducing factor homologous mitochondrion-associated inducer of death

apoptosis-inducing factor-like mitchondrion-associated inducer of

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Aifm2 NCBI NCBI:84883