1. Gene
  2. Ddhd2 - DDHD domain containing 2 Gene

Ddhd2 - DDHD domain containing 2 Gene

种属: Mus musculus

同用名: SAMWD1; mKIAA0725; 2010305K11Rik

基因 ID: 72108 | 基因类型: protein coding

关于 Ddhd2

功能概要

Enables triglyceride Lipase activity. Involved in lipid droplet organization and triglyceride catabolic process. Acts upstream of or within positive regulation of mitochondrial fission. Located in membrane. Used to study hereditary spastic paraplegia 54. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 54. Orthologous to human DDHD2 (DDHD domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Ddhd2 基因产物(2)

mRNA Protein Name
NM_001361595.2 NP_001348524.1 phospholipase DDHD2 isoform 2
NM_028102.2 NP_082378.1 phospholipase DDHD2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables triacylglycerol lipase activity IDA
IDA: 通过直接分析推断
25267624 MGI
enables triacylglycerol lipase activity IMP
IMP: 通过突变表型推断
25267624 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within lipid droplet organization IMP
IMP: 通过突变表型推断
25267624 MGI
involved in lipid droplet organization IMP
IMP: 通过突变表型推断
25267624 MGI
acts upstream of locomotory behavior IMP
IMP: 通过突变表型推断
25267624 MGI
acts upstream of or within locomotory behavior IMP
IMP: 通过突变表型推断
25267624 MGI
acts upstream of mitochondrial fission IMP
IMP: 通过突变表型推断
24599962 MGI
acts upstream of or within positive regulation of mitochondrial fission IMP
IMP: 通过突变表型推断
24599962 MGI
acts upstream of or within triglyceride catabolic process IMP
IMP: 通过突变表型推断
25267624 MGI
involved in triglyceride catabolic process IMP
IMP: 通过突变表型推断
25267624 MGI
acts upstream of visual learning IMP
IMP: 通过突变表型推断
25267624 MGI
acts upstream of or within visual learning IMP
IMP: 通过突变表型推断
25267624 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IDA
IDA: 通过直接分析推断
25267624 MGI
is active in membrane IMP
IMP: 通过突变表型推断
25267624 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

phospholipase DDHD2

DDHD domain-containing protein 2

SAM, WWE and DDHD domain-containing protein 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ddhd2 NCBI NCBI:23259