2. Gene
  3. Tmem175 - transmembrane protein 175 Gene

Tmem175 - transmembrane protein 175 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: mTMEM175; 3010001K23Rik

基因 ID: 72392 | 基因类型: protein coding

关于 Tmem175

功能概要

Enables potassium ion leak channel activity. Involved in lysosome organization; neuron cellular homeostasis; and potassium ion transmembrane transport. Predicted to be integral component of endosome membrane and integral component of lysosomal membrane. Predicted to be active in endosome and lysosome. Orthologous to human TMEM175 (transmembrane protein 175). [provided by Alliance of Genome Resources, Apr 2022]

Tmem175 基因产物(6)

mRNA Protein Name
NM_001163531.1 NP_001157003.1 endosomal/lysosomal potassium channel TMEM175 isoform 2
NM_001163532.1 NP_001157004.1 endosomal/lysosomal potassium channel TMEM175 isoform 1
NM_001359423.1 NP_001346352.1 endosomal/lysosomal potassium channel TMEM175 isoform 1
NM_001359426.1 NP_001346355.1 endosomal/lysosomal potassium channel TMEM175 isoform 3
NM_001359427.1 NP_001346356.1 endosomal/lysosomal potassium channel TMEM175 isoform 4
NM_028223.3 NP_082499.3 endosomal/lysosomal potassium channel TMEM175 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables potassium ion leak channel activity IMP
IMP: 通过突变表型推断
26317472 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in neuron cellular homeostasis IMP
IMP: 通过突变表型推断
33505021 MGI
involved in phagosome-lysosome fusion IMP
IMP: 通过突变表型推断
26317472 MGI
involved in potassium ion transmembrane transport IMP
IMP: 通过突变表型推断
26317472 MGI
involved in regulation of lysosomal lumen pH IMP
IMP: 通过突变表型推断
26317472 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

endosomal/lysosomal potassium channel TMEM175

endosomal/lysomomal potassium channel TMEM175

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-33878 2-PPA Inhibitor 98.18% 否
HY-161949 AP-6 Inhibitor 98.17% 否
HY-RS29457 TMEM175 Monkey Pre-designed siRNA Set A Pre-designed Sets / 否
HY-162666 TMEM175 modulator 1 Modulator / 否
HY-RS14683 TMEM175 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS19555 Tmem175 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS26051 Tmem175 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tmem175 NCBI NCBI:84286
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