2. Gene
  3. Usp47 - ubiquitin specific peptidase 47 Gene

Usp47 - ubiquitin specific peptidase 47 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 4930502N04Rik; A630020C16Rik

基因 ID: 74996 | 基因类型: protein coding

关于 Usp47

功能概要

Predicted to enable WD40-repeat domain binding activity; cysteine-type endopeptidase activity; and thiol-dependent Deubiquitinase. Involved in cellular response to UV. Acts upstream of or within negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage. Predicted to be located in cytoplasm. Predicted to be part of SCF ubiquitin Ligase complex. Predicted to be active in cytosol and nucleus. Orthologous to human USP47 (ubiquitin specific peptidase 47). [provided by Alliance of Genome Resources, Apr 2022]

Usp47 基因产物(4)

mRNA Protein Name
NM_001357952.2 NP_001344881.1 ubiquitin carboxyl-terminal hydrolase 47 isoform 3
NM_001403494.1 NP_001390423.1 ubiquitin carboxyl-terminal hydrolase 47 isoform 4
NM_133758.4 NP_598519.2 ubiquitin carboxyl-terminal hydrolase 47 isoform 2
NM_177249.4 NP_796223.2 ubiquitin carboxyl-terminal hydrolase 47 isoform 1
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to UV IMP
IMP: 通过突变表型推断
19966869 MGI
acts upstream of intrinsic apoptotic signaling pathway in response to DNA damage IMP
IMP: 通过突变表型推断
19966869 MGI
acts upstream of or within negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage IMP
IMP: 通过突变表型推断
19966869 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ubiquitin carboxyl-terminal hydrolase 47

deubiquitinating enzyme 47

ubiquitin specific protease 47

ubiquitin thioesterase 47

ubiquitin thiolesterase 47

ubiquitin-specific-processing protease 47

相关产品

Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-13865 P 22077 Inhibitor 98.07% 否
HY-112937 GNE-6640 Inhibitor 99.91% 否
HY-13487 USP7/USP47 inhibitor Inhibitor 98.58% 否
HY-134817 USP7-IN-8 Inhibitor 99.04% 否
HY-174301 USP7-IN-18 / 否
HY-RS15558 USP47 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-111166 USP7/USP47 inhibitor 1 Inhibitor / 否
HY-RS17715 Usp47 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24180 Usp47 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Usp47 NCBI NCBI:55031
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