1. Gene
  2. Slitrk1 - SLIT and NTRK-like family, member 1 Gene

Slitrk1 - SLIT and NTRK-like family, member 1 Gene

种属: Mus musculus

同用名: 3200001I04Rik

基因 ID: 76965 | 基因类型: protein coding

关于 Slitrk1

功能概要

Acts upstream of or within several processes, including adult behavior; axonogenesis; and positive regulation of synapse assembly. Located in glutamatergic synapse. Is integral component of postsynaptic density membrane. Is expressed in several structures, including alimentary system; central nervous system; eye; limb mesenchyme; and reproductive system. Used to study Gilles de la Tourette syndrome. Human ortholog(s) of this gene implicated in Gilles de la Tourette syndrome and trichotillomania. Orthologous to human SLITRK1 (SLIT and NTRK like family member 1). [provided by Alliance of Genome Resources, Apr 2022]

Slitrk1 基因产物(1)

mRNA Protein Name
NM_199065.2 NP_951020.1 SLIT and NTRK-like protein 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
36085162 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within adult behavior IMP
IMP: 通过突变表型推断
18794888 MGI
acts upstream of or within axonogenesis IDA
IDA: 通过直接分析推断
14550773 MGI
acts upstream of or within endocytosis IMP
IMP: 通过突变表型推断
36085162 MGI
acts upstream of or within gene expression IMP
IMP: 通过突变表型推断
36085162 MGI
acts upstream of or within homeostatic process IMP
IMP: 通过突变表型推断
18794888 MGI
acts upstream of or within multicellular organism growth IMP
IMP: 通过突变表型推断
18794888 MGI
acts upstream of or within nervous system development IMP
IMP: 通过突变表型推断
18794888 MGI
acts upstream of or within neuron projection extension IMP
IMP: 通过突变表型推断
36085162 MGI
acts upstream of or within norepinephrine metabolic process IMP
IMP: 通过突变表型推断
36085162 MGI
acts upstream of or within positive regulation of synapse assembly IDA
IDA: 通过直接分析推断
24613359 MGI
acts upstream of or within vocalization behavior IMP
IMP: 通过突变表型推断
36085162 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
27273464 MGI
is active in glutamatergic synapse IEP
IEP: 通过表达模式推断
27273464 MGI
is active in postsynaptic density membrane IDA
IDA: 通过直接分析推断
27273464 MGI
is active in postsynaptic density membrane IEP
IEP: 通过表达模式推断
27273464 MGI
located in synapse IDA
IDA: 通过直接分析推断
27273464 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

SLIT and NTRK-like protein 1

slit and trk like gene 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slitrk1 NCBI NCBI:114798