2. Gene
  3. ZNF217 - zinc finger protein 217 Gene

ZNF217 - zinc finger protein 217 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：锌指蛋白 217

种属: Homo sapiens

同用名: ZABC1

基因 ID: 7764 | 基因类型: protein coding

关于 ZNF217

Cytogenetic location: 20q13.2 Genomic coordinates (GRCh38): 20:53,567,071-53,597,702 (from NCBI)

This gene has 5 transcripts (splice variants), 197 orthologues and 14 paralogues. Ubiquitous expression in urinary bladder (RPKM 14.5), spleen (RPKM 14.3) and 25 other tissues.

功能概要

启用 DNA 结合转录抑制活性、RNA 聚合酶 II 特异性和 RNA 聚合酶 II 顺式调控区域序列特异性 DNA 结合活性。参与 RNA 聚合酶 II 对转录的负调控。位于线粒体和核斑点。组蛋白脱乙酰酶复合物的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in mitochondrion and nuclear speck. Part of histone deacetylase complex. [provided by Alliance of Genome Resources, Apr 2022]

ZNF217 基因产物(2)

mRNA Protein Name
NM_001385034.1 NP_001371963.1 zinc finger protein 217 isoform 1
NM_006526.3 NP_006517.1 zinc finger protein 217 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
17130829 GOA
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
17130829 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
16940172 GOA
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
18625718 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
16940172 GOA
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
17130829 GOA
involved in regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
18625718 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of histone deacetylase complex IDA
IDA: 通过直接分析推断
18625718 GOA
located in nucleoplasm IDA
IDA: 通过直接分析推断
18625718 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ZNF217 蛋白结构

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (67 - 86)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (128 - 150)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (156 - 178)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (218 - 238)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (376 - 397)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (486 - 508)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1048 a.a.
蛋白主名 其他名称

zinc finger protein 217

ZNF217 抗体

目录号 产品名 应用 反应物种
HY-P82978 ZNF217 Antibody (YA2723) WB Human

关联疾病

疾病名称 别名
Ovarian Serous Cystadenocarcinoma

Serous Cystadenoma

Cystadenoma Serous

Cystadenoma, Serous
Cystadenocarcinoma
Ovarian Cancer

Ovarian Carcinoma

Ovarian Neoplasm

Malignant Tumour Of Ovary

Cancer Of The Ovary

Epithelial Ovarian Cancer

Neoplasm Of Ovary

Ovarian Neoplasms

Ovarian Cancers

Malignant Neoplasm Of Ovary

Primary Malignant Neoplasm Of Ovary

Ovarian Cancer, Somatic

Malignant Ovarian Tumor

Ovary Neoplasm

Primary Ovarian Cancer

Tumor Of The Ovary

Malignant Neoplasm Of The Ovary

Malignant Tumor Of The Ovary

Ovarian Malignant Tumor

OC

Ovarian Carcinomas

Cancer, Ovarian

Cancer Of Ovary

Ovary Cancer

Ca Ovary
Ovarian Clear Cell Carcinoma

Clear-Cell Ovarian Carcinoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16110 ZNF217 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta ZNF217 VGNC VGNC:78874
Canis familiaris ZNF217 VGNC VGNC:48674
Felis catus ZNF217 VGNC VGNC:82318
Rattus norvegicus ZNF217 RGD RGD:1308451
Bos taurus ZNF217 VGNC VGNC:57037
Mus musculus ZNF217 MGD MGI:2685408
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