1. Gene
  2. Aco2 - aconitase 2 Gene

Aco2 - aconitase 2 Gene

种属: Rattus norvegicus

基因 ID: 79250 | 基因类型: protein coding

关于 Aco2

功能概要

Enables 3 iron, 4 sulfur cluster binding activity; 4 iron, 4 sulfur cluster binding activity; and aconitate hydratase activity. Involved in several processes, including response to isolation stress; tricarboxylic acid cycle; and tricarboxylic acid metabolic process. Located in mitochondrion. Human ortholog(s) of this gene implicated in infantile cerebellar-retinal degeneration and optic atrophy 9. Orthologous to human ACO2 (aconitase 2). [provided by Alliance of Genome Resources, Apr 2022]

Aco2 基因产物(1)

mRNA Protein Name
NM_024398.2 NP_077374.2 aconitate hydratase, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 3 iron, 4 sulfur cluster binding IDA
IDA: 通过直接分析推断
14674759 RGD
enables 4 iron, 4 sulfur cluster binding IDA
IDA: 通过直接分析推断
14674759 RGD
enables aconitate hydratase activity IDA
IDA: 通过直接分析推断
9712727 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
15840721 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in citrate metabolic process IDA
IDA: 通过直接分析推断
9712727 RGD
involved in isocitrate metabolic process IDA
IDA: 通过直接分析推断
9712727 RGD
involved in liver development IEP
IEP: 通过表达模式推断
755797 RGD
involved in response to isolation stress IEP
IEP: 通过表达模式推断
19616040 RGD
involved in tricarboxylic acid cycle IDA
IDA: 通过直接分析推断
9712727 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

aconitate hydratase, mitochondrial

aconitase 2, mitochondrial

citrate hydro-lyase

mitochondrial aconitase (nuclear aco2 gene)

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Aco2 NCBI NCBI:50
Mus musculus Aco2 NCBI NCBI:11429