2. Gene
  3. PRRT1 - proline rich transmembrane protein 1 Gene

PRRT1 - proline rich transmembrane protein 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：富脯氨酸的跨膜蛋白 1

种属: Homo sapiens

同用名: NG5; DSPD1; C6orf31; IFITMD7; SynDIG4

基因 ID: 80863 | 基因类型: protein coding

关于 PRRT1

Cytogenetic location: 6p21.32 Genomic coordinates (GRCh38): 6:32,148,363-32,153,083 (from NCBI)

This gene has 5 transcripts (splice variants), 1 gene allele, 130 orthologues and 4 paralogues. Biased expression in brain (RPKM 24.0), ovary (RPKM 12.1) and 6 other tissues.

功能概要

实现相同的蛋白质结合活性。预计参与多个过程，包括长期突触抑制；蛋白质定位于细胞表面；和 AMPA 受体活性的调节。预计在多个过程的上游或内部起作用，包括学习或记忆；长期突触增强；和突触组织。预测位于突触后致密膜和突触小泡膜。预计在谷氨酸能突触和膜中活跃。预计是突触后膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Enables identical protein binding activity. Predicted to be involved in several processes, including long-term synaptic depression; protein localization to cell surface; and regulation of AMPA Receptor activity. Predicted to act upstream of or within several processes, including learning or memory; long-term synaptic potentiation; and synapse organization. Predicted to be located in postsynaptic density membrane and synaptic vesicle membrane. Predicted to be active in glutamatergic synapse and membrane. Predicted to be integral component of postsynaptic membrane. [provided by Alliance of Genome Resources, Apr 2022]

PRRT1 基因产物(2)

mRNA Protein Name
NM_001363780.2 NP_001350709.1 proline-rich transmembrane protein 1 isoform 2
NM_030651.4 NP_085154.3 proline-rich transmembrane protein 1 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PRRT1 蛋白结构

CD225

CD225: Interferon-induced transmembrane protein (216 - 286)

  • 0
  • 100
  • 200
  • 306 a.a.
蛋白主名 其他名称

proline-rich transmembrane protein 1

dispanin subfamily D member 1

关联疾病

疾病名称 别名
Alzheimer Disease 8

Ad8

Alzheimer'S Disease 8

Alzheimer Disease, Familial, 8

Alzheimer Disease, Familial 8

Alzheimer'S Disease 8, Late Onset
Osteogenesis Imperfecta, Type V

Osteogenesis Imperfecta Type 5

OI5

Osteogenesis Imperfecta Type V

Oi Type 5

Oi Type V

Oi, Type V

Oi With Calcification In Interosseous Membranes

Type V Oi

Osteogenesis Imperfecta 5

Oi-V
Delayed Sleep Phase Disorder

Delayed Sleep Phase Syndrome

Delayed Sleep Phase Syndrome, Susceptibility To

DSPD

Delayed Sleep Phase Disorder, Susceptibility To

DSPS

Sleep Phase, Delayed, Disorder

Sleep Phase Syndrome, Delayed, Susceptibility To
Episodic Kinesigenic Dyskinesia 1

Paroxysmal Kinesigenic Choreoathetosis

Paroxysmal Kinesigenic Dyskinesia

Dystonia 10

Familial Paroxysmal Kinesigenic Dyskinesia

Episodic Kinesigenic Dyskinesia

EKD1

Pkc

Pkd

Dyt10

Familial Pkd

Paroxysmal Kinesigenic Choreathetosis

Familial Paroxysmal Dystonia

Dystonia, Familial Paroxysmal

Dyt-Prrt2

Dystonia, Type 10
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-106244 DOTATATE 99.95% 是
HY-106244A DOTATATE acetate 99.77% 否
HY-RS11241 PRRT1 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta PRRT1 VGNC VGNC:83449
Canis familiaris PRRT1 VGNC VGNC:49684
Felis catus PRRT1 VGNC VGNC:102497
Bos taurus PRRT1 VGNC VGNC:50003
Mus musculus PRRT1 MGD MGI:1932118
Rattus norvegicus PRRT1 RGD RGD:1359348
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