2. Gene
  3. Jup - junction plakoglobin Gene

Jup - junction plakoglobin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 81679 | 基因类型: protein coding

关于 Jup

功能概要

Enables protein kinase binding activity. Predicted to be involved in several processes, including cellular response to indole-3-methanol; regulation of heart contraction; and regulation of transcription, DNA-templated. Predicted to act upstream of or within cell-cell adhesion; desmosome assembly; and skin development. Located in several cellular components, including apicolateral plasma membrane; fascia adherens; and lateral plasma membrane. Colocalizes with actin Cytoskeleton. Human ortholog(s) of this gene implicated in cardiomyopathy (multiple); palmoplantar keratosis (multiple); renal cell carcinoma; and reproductive organ Cancer (multiple). Orthologous to human JUP (junction plakoglobin). [provided by Alliance of Genome Resources, Apr 2022]

Jup 基因产物(1)

mRNA Protein Name
NM_031047.2 NP_112309.2 junction plakoglobin
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21062920 RGD
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
12700184 RGD
enables protein tyrosine kinase binding IPI
IPI: 通过物理相互作用推断
12700184 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
8834786 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin cytoskeleton IDA
IDA: 通过直接分析推断
12478657 RGD
located in adherens junction IDA
IDA: 通过直接分析推断
8834786 RGD
located in apicolateral plasma membrane IDA
IDA: 通过直接分析推断
10335358 RGD
located in cell-cell junction IDA
IDA: 通过直接分析推断
12478657 RGD
located in cytoplasmic side of plasma membrane IDA
IDA: 通过直接分析推断
12478657 RGD
located in desmosome IDA
IDA: 通过直接分析推断
16406610 RGD
located in fascia adherens IDA
IDA: 通过直接分析推断
16406610 RGD
located in lateral plasma membrane IDA
IDA: 通过直接分析推断
10335358 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

junction plakoglobin

gamma-catenin (plakoglobin)

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07061 JUP Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18118 Jup Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24592 Jup Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Jup NCBI NCBI:3728
Mus musculus Jup NCBI NCBI:16480
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