2. Gene
  3. TRIM56 - tripartite motif containing 56 Gene

TRIM56 - tripartite motif containing 56 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含三方基序 56

种属: Homo sapiens

同用名: RNF109

基因 ID: 81844 | 基因类型: protein coding

关于 TRIM56

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:101,085,481-101,097,967 (from NCBI)

This gene has 4 transcripts (splice variants), 119 orthologues and 80 paralogues. Ubiquitous expression in spleen (RPKM 9.3), ovary (RPKM 7.5) and 25 other tissues.

功能概要

启用 RNA 结合活性。预计参与多个过程，包括对其他生物体的防御反应；大分子代谢过程的正向调控；和蛋白质 K63 连接的泛素化。预计位于细胞质中。预计在染色质和核质中具有活性。 [由基因组资源联盟提供，2022 年 4 月]

Enables RNA binding activity. Predicted to be involved in several processes, including defense response to Other organism; positive regulation of macromolecule metabolic process; and protein K63-linked ubiquitination. Predicted to be located in cytoplasm. Predicted to be active in chromatin and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TRIM56 基因产物(1)

mRNA Protein Name
NM_030961.3 NP_112223.1 E3 ubiquitin-protein ligase TRIM56
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
22948160 GOA
enables ubiquitin protein ligase activity IDA
IDA: 通过直接分析推断
29426904 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in defense response to virus IDA
IDA: 通过直接分析推断
29426904 GOA
involved in positive regulation of innate immune response IDA
IDA: 通过直接分析推断
29426904 GOA
involved in positive regulation of non-canonical NF-kappaB signal transduction IDA
IDA: 通过直接分析推断
35952808 GOA
involved in positive regulation of type I interferon-mediated signaling pathway IDA
IDA: 通过直接分析推断
29426904 GOA
involved in protein monoubiquitination IDA
IDA: 通过直接分析推断
29426904 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TRIM56 蛋白结构

zf-C3HC4

zf-C3HC4: Zinc finger, C3HC4 type (RING finger) (21 - 59)

zf-B_box

zf-B_box: B-box zinc finger (165 - 205)

  • 0
  • 200
  • 400
  • 600
  • 755 a.a.
蛋白主名 其他名称

E3 ubiquitin-protein ligase TRIM56

RING finger protein 109

TRIM56 抗体

目录号 产品名 应用 反应物种
HY-P81639 TRIM56 Antibody (YA1384) WB, ICC/IF Human

关联疾病

疾病名称 别名
Postinfectious Encephalitis

Postinfective Encephalitis

Secondary Encephalitis
Aicardi-Goutieres Syndrome

Aicardi Goutieres Syndrome

Cree Encephalitis

Aicardi-Goutières Syndrome

Encephalopathy With Basal Ganglia Calcification

Ags

Encephalopathy With Intracranial Calcification And Chronic Lymphocytosis Of Cerebrospinal Fluid

Pseudotoxoplasmosis Syndrome

Encephalopathy, Familial Infantile, With Calcification Of Basal Ganglia And Chronic Cerebrospinal Fluid Lymphocytosis

Familial Infantile Encephalopathy With Intracranial Calcification And Chronic Cerebrospinal Fluid Lymphocytosis

Aicardi-Goutieres Syndrome 1
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15057 TRIM56 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS21963 Trim56 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS28480 Trim56 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus TRIM56 VGNC VGNC:36342
Felis catus TRIM56 VGNC VGNC:103755
Macaca mulatta TRIM56 VGNC VGNC:79173
Mus musculus TRIM56 MGD MGI:2685298
Rattus norvegicus TRIM56 RGD RGD:40958426
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