2. Gene
  3. Dvl1 - dishevelled segment polarity protein 1 Gene

Dvl1 - dishevelled segment polarity protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: dvl-1

基因 ID: 83721 | 基因类型: protein coding

关于 Dvl1

功能概要

Enables protein kinase binding activity and small GTPase binding activity. Involved in several processes, including dendritic spine morphogenesis; positive regulation of excitatory postsynaptic potential; and positive regulation of neuron projection arborization. Located in several cellular components, including dendritic spine; growth cone; and postsynaptic density. Colocalizes with microtubule. Biomarker of myocardial infarction. Human ortholog(s) of this gene implicated in DiGeorge syndrome and autosomal dominant Robinow syndrome 2. Orthologous to human DVL1 (dishevelled segment polarity protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Dvl1 基因产物(1)

mRNA Protein Name
NM_031820.1 NP_114008.1 segment polarity protein dishevelled homolog DVL-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
16478782 RGD
enables small GTPase binding IPI
IPI: 通过物理相互作用推断
15608632 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in Wnt signaling pathway IGI
IGI: 通过遗传相互作用推断
21670302 RGD
involved in dendritic spine morphogenesis IGI
IGI: 通过遗传相互作用推断
21670302 RGD
involved in positive regulation of excitatory postsynaptic potential IGI
IGI: 通过遗传相互作用推断
21670302 RGD
involved in positive regulation of neuron projection arborization IGI
IGI: 通过遗传相互作用推断
25424568 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
15608632 RGD
located in dendrite IDA
IDA: 通过直接分析推断
15608632 RGD
located in dendritic spine IDA
IDA: 通过直接分析推断
21670302 RGD
located in growth cone IDA
IDA: 通过直接分析推断
15608632 RGD
located in microtubule IDA
IDA: 通过直接分析推断
15608632 RGD
located in microtubule cytoskeleton IDA
IDA: 通过直接分析推断
15608632 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
15608632 RGD
located in postsynaptic density IDA
IDA: 通过直接分析推断
21670302 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

segment polarity protein dishevelled homolog DVL-1

DSH homolog 1

dishevelled, dsh homolog 1

dishevelled-1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04076 DVL1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS20720 Dvl1 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS27232 Dvl1 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dvl1 NCBI NCBI:1855
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