2. Gene
  3. ZC3H8 - zinc finger CCCH-type containing 8 Gene

ZC3H8 - zinc finger CCCH-type containing 8 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含锌指 CCCH 型 8

种属: Homo sapiens

同用名: Fliz1; ZC3HDC8

基因 ID: 84524 | 基因类型: protein coding

关于 ZC3H8

This gene has 6 transcripts (splice variants), 94 orthologues and 2 paralogues. Ubiquitous expression in testis (RPKM 3.7), thyroid (RPKM 3.3) and 25 other tissues.

功能概要

启用 RNA 结合活性。参与多个过程，包括胸腺细胞凋亡过程的正调控；转录调控，DNA 模板化；和 snRNA 转录。位于 Cajal 体内；组蛋白基因座体；和转录活性染色质。转录延伸因子复合体的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Enables RNA binding activity. Involved in several processes, including positive regulation of thymocyte apoptotic process; regulation of transcription, DNA-templated; and snRNA transcription. Located in Cajal body; histone locus body; and transcriptionally active chromatin. Part of transcription elongation factor complex. [provided by Alliance of Genome Resources, Apr 2022]

ZC3H8 基因产物(1)

mRNA Protein Name
NM_032494.3 NP_115883.2 zinc finger CCCH domain-containing protein 8
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
23932780 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in T cell homeostasis IMP
IMP: 通过突变表型推断
12153508 GOA
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
12077251 GOA
involved in negative regulation of T cell differentiation in thymus IMP
IMP: 通过突变表型推断
12153508 GOA
involved in positive regulation of thymocyte apoptotic process IMP
IMP: 通过突变表型推断
12153508 GOA
involved in positive regulation of transcription by RNA polymerase III IMP
IMP: 通过突变表型推断
23932780 GOA
involved in response to antibiotic IDA
IDA: 通过直接分析推断
12153508 GOA
involved in snRNA transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
23932780 GOA
involved in snRNA transcription by RNA polymerase III IMP
IMP: 通过突变表型推断
23932780 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Cajal body IDA
IDA: 通过直接分析推断
23932780 GOA
located in euchromatin IDA
IDA: 通过直接分析推断
23932780 GOA
located in histone locus body IDA
IDA: 通过直接分析推断
23932780 GOA
part of transcription elongation factor complex IDA
IDA: 通过直接分析推断
23932780 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ZC3H8 蛋白结构

zf-CCCH

zf-CCCH: Zinc finger C-x8-C-x5-C-x3-H type (and similar) (194 - 216)

zf-CCCH

zf-CCCH: Zinc finger C-x8-C-x5-C-x3-H type (and similar) (222 - 245)

  • 0
  • 100
  • 200
  • 291 a.a.
蛋白主名 其他名称

zinc finger CCCH domain-containing protein 8

zinc finger CCCH-type domain containing 8

关联疾病

疾病名称 别名
Villous Adenocarcinoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15996 ZC3H8 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus ZC3H8 VGNC VGNC:37110
Felis catus ZC3H8 VGNC VGNC:67190
Macaca mulatta ZC3H8 VGNC VGNC:106245
Rattus norvegicus ZC3H8 RGD RGD:1310458
Canis familiaris ZC3H8 VGNC VGNC:48562
Mus musculus ZC3H8 MGD MGI:1930128
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