2. Gene
  3. GJA10 - gap junction protein alpha 10 Gene

GJA10 - gap junction protein alpha 10 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：缝隙连接蛋白α10

种属: Homo sapiens

同用名: CX62

基因 ID: 84694 | 基因类型: protein coding

关于 GJA10

Cytogenetic location: 6q15 Genomic coordinates (GRCh38): 6:89,894,469-89,896,120 (from NCBI)

This gene has 3 transcripts (splice variants), 1 gene allele, 254 orthologues and 20 paralogues.

功能概要

连接蛋白，如 GJA10，参与间隙连接的形成，间隙连接是直接连接接触细胞细胞质的细胞间管道。每个间隙连接通道由 2 个半通道对接形成，每个半通道包含 6 个连接蛋白亚基 (Sohl 等人，2003 [PubMed 12881038]) 。[OMIM 提供，2008 年 3 月]

Connexins, such as GJA10, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008]

GJA10 基因产物(1)

mRNA Protein Name
NM_032602.2 NP_115991.1 gap junction alpha-10 protein

GJA10 蛋白结构

Connexin

Connexin: Connexin (3 - 108)

(167 - 233)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 543 a.a.
蛋白主名 其他名称

gap junction alpha-10 protein

connexin 62

关联疾病

疾病名称 别名
Deafness, Autosomal Dominant 66

DFNA66

Autosomal Dominant Nonsyndromic Deafness 66

Autosomal Dominant Deafness 66

Deafness, Autosomal Dominant, 66
Noonan Syndrome 5

NS5

Noonan Syndrome, Type 5
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05441 GJA10 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus GJA10 MGD MGI:1339969
Felis catus GJA10 VGNC VGNC:62562
Canis familiaris GJA10 VGNC VGNC:41232
Macaca mulatta GJA10 VGNC VGNC:72952
Rattus norvegicus GJA10 RGD RGD:1309630
Bos taurus GJA10 VGNC VGNC:29371
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