2. Gene
  3. RABGAP1L - RAB GTPase activating protein 1 like Gene

RABGAP1L - RAB GTPase activating protein 1 like Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：RAB GTP 酶激活蛋白 1 样

种属: Homo sapiens

同用名: HHL; TBC1D18

基因 ID: 9910 | 基因类型: protein coding

关于 RABGAP1L

Cytogenetic location: 1q25.1 Genomic coordinates (GRCh38): 1:174,159,520-174,995,308 (from NCBI)

This gene has 23 transcripts (splice variants), 277 orthologues and 45 paralogues. Ubiquitous expression in heart (RPKM 7.5), brain (RPKM 5.9) and 25 other tissues.

功能概要

启用 GTPase 激活剂活性和小 GTPase 结合活性。在蛋白质定位的调节上游或调节内起作用。位于高尔基体；早期内体；和核。 [由基因组资源联盟提供，2022 年 4 月]

Enables GTPase activator activity and small GTPase binding activity. Acts upstream of or within regulation of protein localization. Located in Golgi apparatus; early endosome; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

RABGAP1L 基因产物(19)

mRNA Protein Name
NM_001035230.3 NP_001030307.1 rab GTPase-activating protein 1-like isoform B
NM_001243763.2 NP_001230692.1 rab GTPase-activating protein 1-like isoform B
NM_001243764.2 NP_001230693.1 rab GTPase-activating protein 1-like isoform D
NM_001243765.2 NP_001230694.1 rab GTPase-activating protein 1-like isoform C
NM_001330989.2 NP_001317918.1 rab GTPase-activating protein 1-like isoform E
NM_001366445.1 NP_001353374.1 rab GTPase-activating protein 1-like isoform F
NM_001366446.1 NP_001353375.1 rab GTPase-activating protein 1-like isoform G
NM_001366447.1 NP_001353376.1 rab GTPase-activating protein 1-like isoform H
NM_001366448.1 NP_001353377.1 rab GTPase-activating protein 1-like isoform I
NM_001366449.1 NP_001353378.1 rab GTPase-activating protein 1-like isoform J
NM_001366450.1 NP_001353379.1 rab GTPase-activating protein 1-like isoform K
NM_001366451.1 NP_001353380.1 rab GTPase-activating protein 1-like isoform L
NM_001366452.1 NP_001353381.1 rab GTPase-activating protein 1-like isoform M
NM_001366453.1 NP_001353382.1 rab GTPase-activating protein 1-like isoform N
NM_001366454.1 NP_001353383.1 rab GTPase-activating protein 1-like isoform O
NM_001366455.1 NP_001353384.1 rab GTPase-activating protein 1-like isoform P
NM_001366456.1 NP_001353385.1 rab GTPase-activating protein 1-like isoform Q
NM_001366457.1 NP_001353386.1 rab GTPase-activating protein 1-like isoform R
NM_014857.5 NP_055672.3 rab GTPase-activating protein 1-like isoform A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GTPase activator activity IDA
IDA: 通过直接分析推断
16923123 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
20562859 GOA
enables small GTPase binding IDA
IDA: 通过直接分析推断
16923123 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within regulation of protein localization IDA
IDA: 通过直接分析推断
16923123 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
16923123 GOA
located in early endosome IDA
IDA: 通过直接分析推断
16923123 GOA
located in nucleus IDA
IDA: 通过直接分析推断
16923123 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RABGAP1L 蛋白结构

PID

PID: Phosphotyrosine interaction domain (PTB/PID) (135 - 245)

DUF3694

DUF3694: Kinesin protein (290 - 421)

RabGAP-TBC

RabGAP-TBC: Rab-GTPase-TBC domain (542 - 744)

  • 0
  • 200
  • 400
  • 600
  • 815 a.a.
蛋白主名 其他名称

rab GTPase-activating protein 1-like

TBC1 domain family, member 18

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11585 RABGAP1L Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus RABGAP1L RGD RGD:1304620
Mus musculus RABGAP1L MGD MGI:1352507
Macaca mulatta RABGAP1L VGNC VGNC:76528
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z