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  2. 去乙酰化酶抑制剂Cocktail

去乙酰化酶抑制剂Cocktail  (100× in 70% DMSO)

Cat. No.: HY-K0030
Download Inhibitor Cocktail Flyer Manual COA SDS

去乙酰化酶抑制剂Cocktail (100X)用于维持组蛋白和其它非组蛋白乙酰化状态。

去乙酰化酶抑制剂Cocktail

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

Size (Pre-dissolved in DMSO) Price Stock Quantity
Free Sample   Apply now  
1 mL ¥350 In-stock
1 mL × 10 ¥1600 In-stock
1 mL × 50 ¥6400 In-stock
1 mL × 100 ¥10240 In-stock

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  • Description

  • Storage

  • Protocol

  • Components

  • Documentation

Description
& Advantages

Deacetylase Inhibitor Cocktail is a synergistic combination of chemicals designed to preserve the acetylation state of proteins. Lysine acetylation is an important post-translational modification that can affect protein transcription, cell cycle, and signal transduction pathways. The balance between acetyltransferase enzymes and deacetylase enzymes affects chromatin condensation, transcription factor activity and protein aggregation and is of significant interest to researchers. Deacetylation Inhibition Cocktail is a useful tool for investigating these important biological pathways.

MedChemExpress Deacetylase Inhibitor Cocktail (100× in 70% DMSO) is provided as 1 mL vial. Each vial contains 1 mL deacetylase inhibitor cocktail solubilized in 70% DMSO with the following components: Trichostatin A (40 μM), EX-527 (1 mM), Nicotinamide (400 mM), and Sodium Butyrate (200 mM). Each component has specific inhibitory properties. Trichostatin A acts to inhibit class I/II HDAC. EX-527 inhibits SIRT. Nicotinamide acts against class III HDAC. Sodium Butyrate acts against class I/II HDAC.

Storage

Deacetylase Inhibitor Cocktail (100× in 70% DMSO) can be stored at -20°C for 12 months.

Protocol

1. This product can be applied in Western Blotting, Flow Cytometry, and ImmunoFluorescence and etc.

2. Thaw at room temperature, add at 1:100 (v/v) dilution to culture media, recommended incubation times of 16-48 hours, before assaying.

3. One tube of Protease Inhibitor Cocktail is recommended for inhibition of proteases present in cell for Western Blotting.

Components
Ingredient M.Wt 100× Conc. Target
Trichostatin A 302.37 40 μM Class I/II HDAC
EX-527 248.71 1 mM SIRT
Nicotinamide 122.12 400 mM Class III HDAC
Sodium Butyrate 110.09 200 mM Class I/II HDAC
Documentation

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产品名称:
去乙酰化酶抑制剂Cocktail
目录号:
HY-K0030
需求量: