2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. Jingzhaotoxin XI

Jingzhaotoxin XI  (Synonyms: JZTX-XI)

目录号: HY-P5872
产品使用指南

摩尔计算器

Jingzhaotoxin XI (JZTX-XI) 是一种钠电导 (sodium conductance) 抑制剂，IC50 为 124 nM。Jingzhaotoxin XI 减缓中国仓鼠卵巢 (CHO-K1) 细胞中表达的 Nav1.5 的快速失活 (EC50=1.18±0.2 μM)。

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Custom Peptide Synthesis

Jingzhaotoxin XI Chemical Structure

Jingzhaotoxin XI Chemical Structure

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Jingzhaotoxin XI 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Jingzhaotoxin XI (JZTX-XI) is a sodium conductance inhibitor with an IC50 of 124 nM. Jingzhaotoxin XI slows the fast inactivation (EC50=1.18±0.2 μM) of Nav1.5 expressed in Chinese hamster ovary (CHO-K1) cells[1].

IC50 & Target

IC50: 124 nM (sodium conductance)[1]
分子量

3726.27

Formula

C158H234N44O47S7
Sequence

Glu-Cys-Arg-Lys-Met-Phe-Gly-Gly-Cys-Ser-Val-Asp-Ser-Asp-Cys-Cys-Ala-His-Leu-Gly-Cys-Lys-Pro-Thr-Leu-Lys-Tyr-Cys-Ala-Trp-Asp-Gly-Thr-Phe-NH2 (Disulfide bridge: Cys2-Cys16,Cys9-Cys21,Cys15-Cys28)
Sequence Shortening

ECRKMFGGCSVDSDCCAHLGCKPTLKYCAWDGTF-NH2 (Disulfide bridge: Cys2-Cys16,Cys9-Cys21,Cys15-Cys28)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Jingzhaotoxin XI 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Jingzhaotoxin XIJZTX-XISodium ChannelNa channelsNa+ channelsChilobrachys jingzhaoCHO-K1Inhibitorinhibitorinhibit

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