1. Immunology/Inflammation
  2. PD-1/PD-L1
  3. Ledostomig

Ledostomig 是一种免疫球蛋白 (H-γ1-scFv-L-κ) 二聚体单克隆抗体,靶向人神经毡蛋白-5 (NTS5) 和程序性死亡-1 (PD-1)。Ledostomig 有望用于多种癌症的研究。

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CAS No. : 2769743-01-1

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ledostomig is an immunoglobulin (H-γ1-scFv-L-κ) dimer monoclonal antibody targeting human netrin-5 (NTS5) and programmed death-1 (PD-1). Ledostomig is promising for research of various cancers[1].

同型

immunoglobulin (H-gamma1-scFvhk_L-kappa) dimer

IC50 & Target

NT5E & PD-1

基因 ID

4907 & 5133  [NCBI]

Accession

P21589 & Q15116

应用

ELISA, FACS, Functional assay

偶联物

Unconjugated

复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.

CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • IgG1-kappa-[scFv]2-kappa
纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Ledostomig
目录号:
HY-P991147
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