2. Apoptosis
  3. Ferroptosis
  4. Liproxstatin-1 hydrochloride

Liproxstatin-1 hydrochloride 是一种有效的 ferroptosis 抑制剂，抑制 ferroptotic 细胞死亡 (IC50=22 nM)。

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Liproxstatin-1 hydrochloride Chemical Structure

Liproxstatin-1 hydrochloride Chemical Structure

CAS No. : 2250025-95-5

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Liproxstatin-1 hydrochloride 的其他形式现货产品:

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Other Forms of Liproxstatin-1 hydrochloride:

Liproxstatin-1 hydrochloride 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 95 篇科研文献

RT-PCR

    Liproxstatin-1 hydrochloride purchased from MCE. Usage Cited in: Biochem Biophys Res Commun. 2019 Nov 5;519(2):240-245.  [Abstract]

    The ROS and inflammatory cytokines levels increase in acute RILI. The serum levels of inflammatory cytokines increase in RILI. Elisa was used to measure the levels of inflammatory cytokines (TNF-a, IL-6, IL-10 and TGF-b1) at day 15, day 30 and day 60.

    • 生物活性

    • 纯度 & 产品资料

    • 参考文献

    生物活性

    Liproxstatin-1 hydrochloride is a potent ferroptosis inhibitor and inhibits ferroptotic cell death (IC50=22 nM)[1].

    体外研究
    (In Vitro)

    Liproxstatin-1 shows antiferroptotic activity with an IC50 of approximately 38 nM in mouse embryonic fibroblasts[2].

    MCE has not independently confirmed the accuracy of these methods. They are for reference only.

    Liproxstatin-1 hydrochloride 相关抗体:
    体内研究
    (In Vivo)

    Liproxstatin-1 (10 mg/kg, i.p.) suppresses ferroptosis in human cells, Gpx4-/- kidney and in an ischaemia/reperfusion-induced tissue injury model[1].

    MCE has not independently confirmed the accuracy of these methods. They are for reference only.
    分子量

    377.31

    Formula

    C19H22Cl2N4
    CAS 号
    运输条件

    Room temperature in continental US; may vary elsewhere.
    储存方式

    Please store the product under the recommended conditions in the Certificate of Analysis.
    纯度 & 产品资料
    参考文献

    Liproxstatin-1 hydrochloride 相关分类

    • 摩尔计算器

    • 稀释计算器

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    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

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    × = ×
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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Liproxstatin-12250025-95-5Liproxstatin1Liproxstatin 1FerroptosisInhibitorinhibitorinhibit

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    产品名称：
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    目录号：
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