1. Immunology/Inflammation
  2. C-type Lectin-like Receptors (CTLRs) Transmembrane Glycoprotein
  3. Litifilimab

Litifilimab  (Synonyms: BIIB059)

目录号: HY-P9990 纯度: 99.51%
COA 技术支持

Litifilimab (BIIB059) 是一种皮下给药的人源化抗 BDCA2 IgG1 单克隆抗体。Litifilimab 能够抑制 I 型干扰素、细胞因子和趋化因子的产生。Litifilimab 可用于系统性红斑狼疮等疾病的研究。

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CAS No. : 2407378-48-5

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
1 mg ¥3000
In-stock
5 mg ¥6900
In-stock
10 mg   询价  
50 mg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Litifilimab (BIIB059) is a humanized anti-BDCA2 IgG1 monoclonal antibody administered subcutaneously. Litifilimab can inhibit the production of type I interferons, cytokines and chemokines. Litifilimab can be used in the research of diseases such as systemic lupus erythematosus[1][2].

同型

Human IgG1 kappa

推荐同型对照抗体
种属

Humanized

IC50 & Target

C-type lectin domain family 4 member C, CLEC4C

Clinical Trial
应用

ELISA, FACS, Functional assay

偶联物

Unconjugated

复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.

分子量

146.6 kDa

CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • Human IgG1 kappa
Biological Activity
  • Immobilized CLEC4C Protein, Human can bind Litifilimab. The EC50 for this effect is 19.73 ng/mL.
纯度 & 产品资料

纯度: 99.51%

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Litifilimab
目录号:
HY-P9990
需求量: