1. Metabolic Enzyme/Protease
  2. Apolipoprotein
  3. Lp(a)-IN-5

Lp(a)-IN-5 (Compound A) 是一种具有口服活性的脂蛋白 (a) (Lp(a)) 抑制剂。Lp(a)-IN-5 抑制 Apo(a) 和 ApoB 蛋白的组装,IC50 值为 0.41 nM。Lp(a)-IN-5 有望用于血浆 Lp(a) 水平升高相关疾病的研究,如心血管疾病。

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Lp(a)-IN-5 Chemical Structure

Lp(a)-IN-5 Chemical Structure

CAS No. : 2924841-79-0

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查看 Apolipoprotein 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lp(a)-IN-5 (Compound A) is an orally active lipoprotein (a) (Lp(a)) inhibitor. Lp(a)-IN-5 inhibits the assembly of Apo(a) and ApoB proteins with an IC50 value of 0.41 nM. Lp(a)-IN-5 is promising for research of diseases related to elevated plasma Lp(a) levels, such as cardiovascular diseases[1].

分子量

740.93

Formula

C43H56N4O7

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Lp(a)-IN-5
目录号:
HY-171464
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