2. Metabolic Enzyme/Protease
  3. Phosphorylase
  4. m-APTA

m-APTA  (Synonyms: 5′-S-(3-Aminophenyl)-5′-thioadenosine)

目录号: HY-W750643
产品使用指南 技术支持

m-APTA (5'-S-(3-aminophenyl)-5'-thioadenosine) 是一种选择性化学保护剂，靶向甲基硫代腺苷磷酸化酶 (MTAP)。m-APTA 可以转化为腺嘌呤，这是保护正常细胞免受核碱基类似物 (NBA) 毒性的关键步骤。m-APTA 有望用于 MTAP 缺陷癌症的研究。

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m-APTA Chemical Structure

m-APTA Chemical Structure

CAS No. : 86072-47-1

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m-APTA 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

m-APTA (5'-S-(3-aminophenyl)-5'-thioadenosine) is a selective chemoprotective agent targeting methylthioadenosine phosphorylase (MTAP). m-APTA can be converted into adenine, which is a crucial step in protecting normal cells from the toxicity of nucleobase analogues (NBA). m-APTA is promising for research of MTAP-deficient cancers[1].

分子量

374.42

同用名

5′-S-(3-Aminophenyl)-5′-thioadenosine

Formula

C16H18N6O3S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

m-APTA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

m-APTA86072-47-15′-S-(3-Aminophenyl)-5′-thioadenosinePhosphorylaseMTAPadenineMTAP-deficient cancersInhibitorinhibitorinhibit

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