2. Academic Validation
  3. Manganese displacement from Zinpyr-1 allows zinc detection by fluorescence microscopy and magnetic resonance imaging

Manganese displacement from Zinpyr-1 allows zinc detection by fluorescence microscopy and magnetic resonance imaging

  • Chem Commun (Camb). 2010 Jun 21;46(23):4139-41. doi: 10.1039/c0cc00179a.
Youngmin You 1,  Elisa Tomat,  Kevin Hwang,  Tatjana Atanasijevic,  Wonwoo Nam,  Alan P Jasanoff,  Stephen J Lippard
Affiliations

Affiliation

  • 1 Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
PMID: 20454746 DOI: 10.1039/c0cc00179a
Abstract

A paramagnetic manganese complex of a fluorescein-based probe affords a dual-modality zinc sensor featuring an improved fluorescence dynamic range and an MRI readout.

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