1. Apoptosis
  2. Bcl-2 Family
  3. Mcl1-IN-9

Mcl1-IN-9 

目录号: HY-128607
产品使用指南

Mcl1-IN-9 是一种有效的髓细胞白血病基因 1 (Mcl-1) 抑制剂,在重组的 BCR-ABL+ B-ALL 细胞中的 IC50 值为 446 nM,Ki 值为 0.03 nM。

MCE 的所有产品仅用作科学研究,我们不为任何个人用途提供产品和服务

Mcl1-IN-9 Chemical Structure

Mcl1-IN-9 Chemical Structure

CAS No. : 1810769-31-3

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

Size Stock
100 mg Get quote
250 mg Get quote
500 mg Get quote

* Please select Quantity before adding items.

Customer Review

Top Publications Citing Use of Products
  • 生物活性

  • 技术信息

  • 纯度 & 产品资料

  • 参考文献

Description

Mcl1-IN-9 is a potent myeloid cell leukemia-1 (Mcl-1) Inhibitor with an IC50 of 446 nM in reengineered BCR-ABL+ B-ALL cells and a Ki of 0.03 nM[1].

IC50 & Target[1]

Mcl-1

0.03 nM (Ki)

In Vitro

Mcl1-IN-9 inhibits growth of Mcl-1 dependent tumor cell lines in the nanomolar range[1].

In Vivo

Mcl1-IN-9 inhibits the growth of hematological and triple negative breast cancer xenografts at well tolerated doses[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

639.18

Formula

C₃₇H₃₉ClN₄O₄

CAS No.

1810769-31-3

SMILES

O=C1C2=C(CCCOC3=CC(C)=C(Cl)C(C)=C3)C4=CC=CC(C5=C(C)N(C)N=C5C)=C4N2CCCN1CC6=CC=CC(C(O)=O)=C6

Shipping

Room temperature in continental US; may vary elsewhere

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Mcl1-IN-9
目录号:
HY-128607
需求量:

Mcl1-IN-9

Cat. No.: HY-128607