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  4. Methyltetrazine-amido-bis-(carboxyethoxymethyl)-methane

Methyltetrazine-amido-bis-(carboxyethoxymethyl)-methane 

目录号: HY-W800721
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Methyltetrazine-amido-bis-(carboxyethoxymethyl)-methane 是一种点击化学 PEG 试剂，含有三个羧酸基团和一个甲基四嗪基团。该试剂可与含 TCO 的化合物反应形成稳定的共价键，无需 Cu 催化或高温。TCO 与四嗪的逆电子需求 Diels-Alder 环加成反应是最快的生物正交反应，具有极高的选择性。在活化剂（例如 EDC 或 HATU）存在下，末端羧酸可与一级胺基团反应形成稳定的酰胺键。

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Methyltetrazine-amido-bis-(carboxyethoxymethyl)-methane Chemical Structure

Methyltetrazine-amido-bis-(carboxyethoxymethyl)-methane Chemical Structure

CAS No. : 2698339-32-9

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Methyltetrazine-amido-bis-(carboxyethoxymethyl)-methane 相关抗体

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  • 生物活性

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生物活性

Methyltetrazine-amido-bis-(carboxyethoxymethyl)-methane is a click chemistry PEG reagent which contains three carboxylic acid groups and a methyltetrazine group. This reagent can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

分子量

447.44

Formula

C20H25N5O7
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Methyltetrazine-amido-bis-(carboxyethoxymethyl)-methane 相关分类

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Keywords:

Methyltetrazine-amido-bis-(carboxyethoxymethyl)-methane2698339-32-9Biochemical Assay ReagentsInhibitorinhibitorinhibit

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