2. JAK/STAT Signaling PI3K/Akt/mTOR Protein Tyrosine Kinase/RTK
  3. EGFR PI3K
  4. MTX-241F

MTX-241F 是一种选择性的小分子抑制剂，靶向 EGFR 和 PI3 激酶家族成员。MTX-241F 能够穿透血脑屏障并长期控制肿瘤生长。MTX-241F 在患者来源的 DIPG 神经球中表现出放射增敏活性，可用于弥漫性内源性桥脑胶质瘤 (DIPG) 的研究。

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MTX-241F Chemical Structure

MTX-241F Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

MTX-241F 相关抗体

Top Publications Citing Use of Products

查看 EGFR 亚型特异性产品:

查看所有亚型
EGFR/ErbB1/HER1 ErbB2/HER2 ErbB3/HER3 ErbB4/HER4

查看 PI3K 亚型特异性产品:

查看所有亚型
PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MTX-241F is a selective small molecule inhibitor targeting EGFR and PI3 kinase family members. MTX-241F is able to penetrate the blood-brain barrier and control tumor growth over the long term. MTX-241F exhibits radiosensitizing activity in patient-derived DIPG neurospheres and may be used in the study of diffuse intrinsic pontine glioma (DIPG)[1].

分子量

392.82

Formula

C20H14ClFN6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MTX-241F 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MTX-241FEGFRPI3KEpidermal growth factor receptorErbB-1HER1Phosphoinositide 3-kinaseBrain permeabilityPatient-derived DIPG neurospheresDiffuse endogenous pontine gliomaInhibitorinhibitorinhibit

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产品名称：
MTX-241F
目录号：
HY-149556
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