2. Others GPCR/G Protein Neuronal Signaling
  3. Reference Standards 5-HT Receptor
  4. Naratriptan hydrochloride (Standard)

Naratriptan hydrochloride (Standard)  (Synonyms: 盐酸那拉曲坦 (Standard); GR-85548A hydrochloride (Standard))

目录号: HY-B0197AR 纯度: ≥98%
产品使用指南 技术支持

Naratriptan (GR-85548A) hydrochloride (Standard) 是 Naratriptan hydrochloride (HY-B0197A) 的分析标准品。本产品用于研究及分析应用。Naratriptan (GR-85548A) 是一种选择性 5-HT1B/1D 受体激动剂。Naratriptan 具有外周活性和较好的口服生物利用度，通过激活 5-HT1B/1D 受体诱导颅动脉血管收缩 (对狗基底动脉的 EC50=0.11 μM)。Naratriptan 还抑制三叉神经介导的硬脑膜神经源性血浆外渗，减轻无菌性炎症。Naratriptan 主要用于急性偏头痛的研究，靶向颅血管和神经炎症机制。

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Naratriptan hydrochloride (Standard) Chemical Structure

Naratriptan hydrochloride (Standard) Chemical Structure

CAS No. : 143388-64-1

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规格 价格 是否有货 数量
5 mg ￥700
3 - 5 周
10 mg ￥1120
3 - 5 周
25 mg ￥2250
3 - 5 周
50 mg ￥3400
3 - 5 周
100 mg ￥5000
3 - 5 周
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

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生物活性

Naratriptan (GR-85548A) hydrochloride (Standard) is the analytical standard of Naratriptan hydrochloride (HY-B0197A). This product is intended for research and analytical applications. Naratriptan is a selective 5-HT1B/1D receptor agonist. Naratriptan is peripherally active and has good oral bioavailability, inducing cranial artery vasoconstriction by activating 5-HT1B/1D receptors (EC50=0.11 μM for dog basilar artery). Naratriptan also inhibits trigeminal nerve-mediated dural neurogenic plasma extravasation and reduces sterile inflammation. Naratriptan is mainly used in the research of acute migraine, targeting cranial vascular and neuroinflammatory mechanisms.

分子量

371.93

同用名

盐酸那拉曲坦 (Standard); GR-85548A hydrochloride (Standard)

Formula

C17H26ClN3O2S
CAS 号
中文名称

盐酸那拉曲坦 (Standard)；盐酸纳拉曲坦 (Standard)
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Naratriptan hydrochloride (Standard) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Naratriptan hydrochloride (Standard)143388-64-1GR-85548A hydrochloride (Standard)盐酸那拉曲坦 (Standard)盐酸纳拉曲坦 (Standard)Reference Standards5-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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