2. MAPK/ERK Pathway
  3. MNK
  4. NUCC-0200808

NUCC-0200808 (Compound 12g) 是一种 MNK1 抑制剂，IC50 为 42 nM。NUCC-0200808 可降低 AML 细胞中 eIF4E 磷酸化及其细胞活力，并诱导其凋亡 (Apoptosis)。NUCC-0200808 有望用于白血病领域研究。

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NUCC-0200808 Chemical Structure

NUCC-0200808 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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NUCC-0200808 相关抗体

Top Publications Citing Use of Products

查看 MNK 亚型特异性产品:

查看所有亚型
MNK1 MNK2 MNK

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NUCC-0200808 (Compound 12g) is an inhibitor of MNK1 with an IC50 of 42 nM. NUCC-0200808 reduces eIF4E phosphorylation and cell viability in AML cells, and induces apoptosis. NUCC-0200808 holds promise for research in the field of leukemia[1].

IC50 & Target

MNK1

 

MNK2

 

分子量

315.76

Formula

C15H14ClN5O
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

NUCC-0200808 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NUCC-0200808NUCC0200808NUCC 0200808MNKMitogen activated protein kinase interacting kinaseMAP kinase interacting kinaseMAPK interacting kinaseInhibitorinhibitorinhibit

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产品名称：
NUCC-0200808
目录号：
HY-172457
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