1. GPCR/G Protein
  2. Endothelin Receptor
  3. PD 156252

PD 156252 是一种高效的内皮素 (ET) 拮抗剂的六肽。PD 156252 对兔 ETA 和大鼠 ETB 受体亚型具有增强的结合亲和力,IC50 值分别为 1.0 和 40 nM。

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Custom Peptide Synthesis

PD 156252 Chemical Structure

PD 156252 Chemical Structure

CAS No. : 175592-65-1

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PD 156252 is a hexapeptide that is a highly potent endothelin (ET) antagonist. PD 156252 has enhanced binding affinity for rabbit ETA and rat ETB receptor subtypes with IC50 values of 1.0 and 40 nM, respectively.

分子量

964.16

Formula

C53H69N7O10

CAS 号
Sequence

Ac-{d-Bhg}-Leu-Asp-Ile-{(N-Me)Ile}-Trp

Sequence Shortening

Ac-{d-Bhg}-LDI-{(N-Me)Ile}-W

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

PD 156252 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
PD 156252
目录号:
HY-P10151
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