1. Immunology/Inflammation
  2. Toll-like Receptor (TLR)
  3. PTD-N5-1

PTD-N5-1 (N5-1) 是一种 IRF5 抑制肽。 PTD-N5-1 可阻断 β-葡聚糖诱导的 IL-12IFN-γ 启动的野生型和 Clec2d 缺陷型骨髓源性树突状细胞 (BMDC) 中的产生。PTD-N5-1 通过抑制 IRF5 介导的 IL-12 产生来调节抗真菌免疫。

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PTD-N5-1 Chemical Structure

PTD-N5-1 Chemical Structure

CAS No. : 2088834-68-6

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查看 Toll-like Receptor (TLR) 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PTD-N5-1 (N5-1) is an IRF5 inhibitory peptide. PTD-N5-1 blocks β-glucan-induced IL-12 production in IFN-γ primed wild-type and Clec2d-difecient bone-marrow-derived dendritic cells (BMDCs). PTD-N5-1 regulates antifungal immunity through suppression of IRF5-mediated IL-12 production[1].

分子量

3267.95

Formula

C148H248N52O30S

CAS 号
Sequence

Asp-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Pro-Arg-Arg-Val-Arg-Leu-Lys

Sequence Shortening

DRQIKIWFQNRRMKWKKPRRVRLK

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

产品名称:
PTD-N5-1
目录号:
HY-P11003
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