1. Antibody-drug Conjugate/ADC Related Immunology/Inflammation
  2. ADC Antibody Transmembrane Glycoprotein
  3. Raludotatug

Raludotatug 

目录号: HY-P990028 纯度: 99.00%
COA 技术支持

Raludotatug 是一种人源化抗 CDH6 IgG1 单克隆抗体。Raludotatug 具有抗肿瘤的活性。Raludotatug 可用于合成 ADC 分子 Raludotatug deruxtecan (HY-164734)。

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CAS No. : 2610074-56-9

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规格 价格 是否有货 数量
1 mg ¥3000
In-stock
5 mg ¥7500
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Raludotatug is a humanized anti-CDH6 IgG1 monoclonal antibody. Raludotatug has antitumor activity and can be used to synthesize the ADC molecule Raludotatug deruxtecan (HY-164734)[1].

同型

Human IgG1 kappa

推荐同型对照抗体
种属

Humanized

IC50 & Target

CDH6

体外研究
(In Vitro)

ADC 分子 Raludotatug deruxtecan (HY-164734) 是由人源化抗 CDH6 IgG1 单克隆抗体 Raludotatug、可裂解 GGFG 四肽连接子及拓扑异构酶 I 抑制剂 DXd (HY-13631D) 组成。Raludotatug deruxtecan 可用于卵巢癌和肾癌等肿瘤的研究[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
基因 ID

102144314  [NCBI]

Accession

G7MUQ7/XP_005556691

应用

ELISA, FACS, Functional assay

偶联物

Unconjugated

复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.

分子量

145.702 kDa

CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • Human IgG1 kappa
Biological Activity
  • Immobilized Human CDH6/K-Cadherin, His Tag can bind Raludotatug. The EC50 for this effect is 11.54 ng/mL.
纯度 & 产品资料

纯度: 99.00%

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Raludotatug
目录号:
HY-P990028
需求量: