2. Anti-infection
  3. HBV
  4. Rapavir

Rapavir (JH-B10) 是一种选择性和有效的牛磺胆酸钠共转运多肽 (NTCP) 抑制剂，牛磺胆酸-d4 (TCA-d4) 摄取的 IC50 值为 1.8 nM。Rapavir 在 HBV 感染阶段通过直接与 NTCP 结合并阻断病毒进入细胞发挥抗病毒活性。Rapavir 有望用于 HBV 感染的研究。

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Rapavir Chemical Structure

Rapavir Chemical Structure

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Rapavir 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Rapavir (JH-B10) is a selective and potent sodium taurocholate cotransporting polypeptide (NTCP) inhibitor with an IC50 value of 1.8 nM for the uptake of taurocholic acid-d4 (TCA-d4). Rapavir exerts antiviral activity by directly binding to NTCP and blocking the entry of the virus into cells during the HBV infection phase. Rapavir is promising for research of HBV infections[1].

分子量

1239.38

同用名

JH-B10

Formula

C68H79FN6O15
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Rapavir 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RapavirJH-B10HBVHepatitis B virusNTCPTCA-d4HBV infectionInhibitorinhibitorinhibit

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产品名称：
Rapavir
目录号：
HY-172835
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