1. 重组蛋白
  2. CD Antigens Receptor Proteins
  3. Dendritic Cell CD Proteins
  4. MSR1/CD204
  5. CD204/MSR1 蛋白, Rat (HEK293, Fc)

CD204/MSR1 蛋白, Rat (HEK293, Fc)

目录号: HY-P76783
产品使用指南

CD204/MSR1 蛋白是一种同源三聚体跨膜糖蛋白,在多种病理生理过程中发挥关键的炎症作用。MSR1 在肺、动脉和脂肪组织中高表达。CD204/MSR1 蛋白, Rat (HEK293, Fc) 是重组的 CD204/MSR1 蛋白,由 HEK293 表达,带有 N-hFc 标签。CD204/MSR1 蛋白, Rat (HEK293, Fc) 全长 376 个氨基酸,分子量约为 ~89 kDa。

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描述

CD204/MSR1 Protein is a homo-trimeric transmembrane glycoprotein, holds key inflammatory roles in multiple pathophysiologic processes. MSR1 is highly expressed in lung, arteries, and adipose tissue[1]. CD204/MSR1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD204/MSR1 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CD204/MSR1 Protein, Rat (HEK293, Fc) is 376 a.a., with molecular weight of ~89 kDa.

研究背景

MSR1,也称为清道夫受体-A (SR-A) 或分化簇 204 (CD204),在多种病理生理过程中发挥关键的炎症作用。这种受体主要存在于各种类型的巨噬细胞的表面,它对动脉粥样硬化、先天性和适应性免疫、肺和肝疾病以及最近的癌症等过程产生不同的影响。MSR1 已被证明对 M2 极化很重要。因此,它所承载的作用或MSR1部分取决于表达MSR1的巨噬细胞的类型和巨噬细胞所处的位置。MSR1 的作用通常是二分的,要么保护宿主,要么损害疾病的发病机制[1]

种属

Rat

表达系统

HEK293

标签

N-hFc

蛋白编号

D3ZDS2 (W79-S454)

基因 ID

498638  [NCBI]

蛋白结构
N-term
hFc
MSR1 (W79-S454)
Accession # D3ZDS2
C-term
同用名
Macrophage scavenger receptor types I and II; SCARA1
分子量

Approximately 89 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

CD204/MSR1 Protein, Rat (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CD204/MSR1 Protein, Rat (HEK293, Fc)
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HY-P76783
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