2. 重组蛋白
  3. Cytokines and Growth Factors Immune Checkpoint Proteins CD Antigens
  4. TNF Superfamily Stimulatory Immune Checkpoint Molecules T Cell CD Proteins Macrophage CD Proteins
  5. TNF Superfamily Ligands CD40 Ligand/CD154
  6. CD40 Ligand
  7. CD40L/CD154/TRAP 蛋白, Rabbit (P. pastoris, His)

CD40L/CD154/TRAP 蛋白, Rabbit (P. pastoris, His)

目录号: HY-P700554
产品使用指南

CD40L/CD154/TRAP 蛋白是一种细胞因子，作为 CD40/TNFRSF5 配体，刺激 T 细胞增殖和细胞因子产生。它还促进免疫球蛋白类别转换并与整合素 ITGA5:ITGB1 和 ITGAV:ITGB3 结合。CD40-CD40LG 信号传导需要整合素和 CD40 受体，从而产生细胞类型依赖性效应，如 B 细胞激活、NF-κ-B 信号传导和抗凋亡信号传导。CD40L/CD154/TRAP 蛋白, Rabbit (P. pastoris, His) 是重组的 CD40L/CD154/TRAP 蛋白，由 P. pastoris 表达，带有 N-6*His 标签。CD40L/CD154/TRAP 蛋白, Rabbit (P. pastoris, His) 全长 149 个氨基酸，分子量为 18.2 kDa。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

CD40L/CD154/TRAP Protein, a cytokine, acts as a CD40/TNFRSF5 ligand, stimulating T-cell proliferation and cytokine production. It also facilitates immunoglobulin class switching and binds to integrins ITGA5:ITGB1 and ITGAV:ITGB3. CD40-CD40LG signaling requires both integrins and the CD40 receptor, leading to cell-type dependent effects like B-cell activation, NF-kappa-B signaling, and anti-apoptotic signaling. CD40L/CD154/TRAP Protein, Rabbit (P. pastoris, His) is the recombinant Rabbit-derived CD40L/CD154/TRAP protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of CD40L/CD154/TRAP Protein, Rabbit (P. pastoris, His) is 149 a.a., with molecular weight of 18.2 kDa.
研究背景

CD40L/CD154/TRAP 蛋白是一种细胞因子，充当 CD40/TNFRSF5 的配体。它在共刺激 T 细胞增殖和细胞因子产生中发挥着至关重要的作用。此外，它还参与免疫球蛋白类别转换。CD40L/CD154/TRAP 蛋白充当整合素的配体，特别是 ITGA5:ITGB1 和 ITGAV:ITGB3。CD40-CD40LG 信号传导的激活需要整合素和 CD40 受体，并且该信号传导途径具有细胞类型依赖性效应，包括 B 细胞激活、NF-κ-B 信号传导和抗凋亡信号传导。
种属

Rabbit
表达系统

P. pastoris
标签

N-6*His
蛋白编号

G1SKP7 (M113-L261)
基因 ID

100358388  [NCBI]
蛋白结构
N-term
6*His
CD40L (M113-L261)
Accession # G1SKP7
C-term
同用名
rHuCD40L; CD154; TRAP; TNFSF5; CD40LG; CD40-L
氨基酸序列

MQKGDQDPQIAAHLISEASSKSSSVLQWAKKGYYTMSNTLVTLENGKQLKVKRQGFYYIYAQVTFCSNQEPSSQAPFIASLCLKSSGGSERILLRAANARSSSKTCEQQSIHLGGVFELQADASVFVNVTDASQVNHGTGFTSFGLLKL

分子量

18.2 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

CD40L/CD154/TRAP Protein, Rabbit (P. pastoris, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
CD40L/CD154/TRAP Protein, Rabbit (P. pastoris, His)
目录号：
HY-P700554
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z