2. 重组蛋白
  3. Receptor Proteins
  4. Pattern Recognition Receptors
  5. C-type Lectin Receptors
  6. Collectin-12
  7. CL-P1/COLEC12 蛋白, Rhesus Macaque (sf9, His)

CL-P1/COLEC12 蛋白, Rhesus Macaque (sf9, His)

目录号: HY-P77341
产品使用指南

Collectin-12 是 Ca2+ 依赖的 c 型凝集素家族，含有胶原结构域，作为病原体分子模式的识别分子(1 - 4)。CL-P1/COLEC12 蛋白, Rhesus Macaque (sf9, His) 是重组的 CL-P1/COLEC12 蛋白，由 Sf9 insect cells 表达，带有 N-His 标签。CL-P1/COLEC12 蛋白, Rhesus Macaque (sf9, His) 全长 642 个氨基酸，分子量约为 ~72.3 KDa。

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描述

Collectin-12 is a family of Ca2+-dependent, C-type lectins that contain a collagenous domain and function as recognition molecules for molecular patterns found on pathogens (1 - 4). CL-P1/COLEC12 Protein, Rhesus Macaque (sf9, His) is the recombinant Rhesus Macaque-derived CL-P1/COLEC12 protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of CL-P1/COLEC12 Protein, Rhesus Macaque (sf9, His) is 642 a.a., with molecular weight of ~72.3 KDa.
研究背景

Collectin-12 仅在先天免疫保护中对某些临床重要病原体起重要作用，而且在清除宿主分子、白细胞募集和肿瘤转移中起重要作用。Collectin-12 已被证明与阿尔茨海默病和多发性硬化症病变发展等人类疾病的发病机制有关。Collectin-12 在体外对选定的真菌病原体显示出不同的结合能力。
种属

Rhesus Macaque
表达系统

Sf9 insect cells
标签

N-His
蛋白编号

F6RUR9 (A86-L727)
基因 ID

/
蛋白结构
N-term
His
CL-P1 (A86-L727)
Accession # F6RUR9
C-term
同用名
Collectin-12; Nurse cell scavenger receptor 2; CL-P1; Nsr2
分子量

Approximately 72.3 kDa.
纯度

Greater than 95% as determined by reducing SDS-PAGE
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

CL-P1/COLEC12 Protein, Rhesus Macaque (sf9, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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