CMG-2/ANTXR2 蛋白, Mouse (HEK293, His)

CMG-2/ANTXR2 is essential for cell adhesion and communication with laminin and the extracellular matrix. It exhibits specific binding to laminin, emphasizing its role in laminin-dependent cellular processes. CMG-2/ANTXR2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CMG-2/ANTXR2 protein, expressed by HEK293 , with C-His labeled tag. The total length of CMG-2/ANTXR2 Protein, Mouse (HEK293, His) is 318 a.a., with molecular weight of ~32 KDa.

CMG-2/ANTXR2 蛋白对于细胞与层粘连蛋白和细胞外基质的相互作用是不可或缺的，这表明它在介导细胞与其周围环境之间的粘附和通讯中发挥着关键作用。该蛋白质对层粘连蛋白表现出特异性结合亲和力，强调其参与层粘连蛋白依赖性细胞过程的调节。此外，有人认为与 IV 型胶原蛋白有潜在的相互作用，从而扩大了其与细胞外基质关键成分的结合范围。CMG-2/ANTXR2 与层粘连蛋白和可能的 IV 型胶原蛋白结合的能力强调了其在细胞粘附和基质相关功能中的重要性，有助于形成组织内细胞相互作用的复杂框架。

Measured by its binding ability in a functional ELISA. Immobilized anthrax protective antigen (PA) at 1.5 µg/mL can bind Mouse CMG-2. The ED₅₀ for this effect is 1.329 μg/mL.

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  Measured by its binding ability in a functional ELISA. Immobilized anthrax protective antigen (PA) at 1.5 µg/mL can bind Mouse CMG-2. The ED₅₀ for this effect is 1.329 μg/mL.

Mouse

HEK293

C-His

Q6DFX2 (Q32-G318)

71914  [NCBI]

QAQEQPSCKKAFDLYFVLDKSGSVANNWIEIYNFVHQLTERFVSPEMRLSFIVFSSQATIILPLTGDRYKIGKGLEDLKAVKPVGETYIHEGLKLANEQIQNAGGLKASSIIIALTDGKLDGLVPSYAENEAKKSRSLGASVYCVGVLDFEQAQLERIADSKDQVFPVKGGFQALKGIINSILAQSCTEILELSPSSVCVGEKFQVVLTGRAVTSISHDGSVLCTFTANSTYTKSEKPVSIQPSSILCPAPVLNKDGETLEVSISYNDGKSAVSRSLTITATECTNG

Approximately 32 kDa.

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.