CYTL1 蛋白, Mouse (HEK293, Fc)

CYTL1 is a cytokine-like protein specifically expressed in bone marrow and cord blood mononuclear cells that bear the CD34 surface marker. CYTL1 exhibits specific expression in CD34+ hematopoietic cells, indicating its selective presence within this subset of cells involved in the regulation of hematopoiesis. CYTL1 regulates chondrogenesis and is required for the maintenance of cartilage homeostasis and, in addition, may act as a regulator of embryo implantation in early pregnancy. CYTL1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CYTL1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CYTL1 Protein, Mouse (HEK293, Fc) is 114 a.a., with molecular weight of 48-52 kDa.

CYTL1 是一种细胞因子样蛋白，在带有 CD34 表面标记的骨髓和脐带血单核细胞中特异性表达。CYTL1 在 CD34+ 造血细胞中表现出特异性表达，表明其选择性存在于参与造血调节的细胞亚群中。这种靶向表达模式表明 CYTL1 在 CD34+ 造血细胞的维持或分化中具有潜在作用，强调了它在控制血细胞发育和稳态的复杂分子过程网络中的重要性。CYTL1 与 CD34+ 细胞的特异性关联意味着可能参与造血干细胞或祖细胞功能，进一步强调了其在造血精细调节机制中的相关性。CYTL1 调节软骨形成，是维持软骨稳态所必需的，此外，还可作为妊娠早期胚胎植入的调节剂^[1][2]。

Mouse

HEK293

C-hFc

A1E5L0 (A26-S139)

231162  [NCBI]

APPTCYSRMLTLSREIMADFQSLQASEPEDSCVRYLPRLYLDIHNYCVLAKLRDFVASPQCWKMAEVDTLKDRVRKLYTIMNSFCRRDLVFLSDDCSALEDPIPEATGPPDWQS

48-52 kDa

Greater than 95% as determined by Tris-Bis PAGE.

无菌粉末.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.