DSC3/Desmocollin-3 蛋白, Mouse (Cell-Free, His)

DSC3 is a component of intercellular desmosome junctions and plays a key role in orchestrating complex interactions between plaque proteins and intermediate filaments, thereby promoting strong cell-to-cell adhesion. In addition to its adhesive function, DSC3 emerges as a potential contributor to epidermal cell localization, particularly in the context of cell stratification. DSC3/Desmocollin-3 Protein, Mouse (Cell-Free, His) is the recombinant mouse-derived DSC3/Desmocollin-3 protein, expressed by E. coli Cell-free , with N-10*His labeled tag.

Desmocollin-3 (DSC3) 是细胞间桥粒连接的重要组成部分，对于介导细胞间粘附至关重要。DSC3 在这些连接处发挥作用，促进斑块蛋白和中间丝之间的相互作用，在组织的结构完整性和稳定性中发挥着至关重要的作用。值得注意的是，DSC3 可能通过介导表达不同亚型的细胞之间的差异粘附性来促进表皮细胞的定位和分层。这表明它参与表皮层内细胞排列的调节。DSC3 的多方面功能强调了其在细胞粘附过程和组织组织中的重要性，强调了其在维持各种组织的适当结构和功能中的作用。（参考：提供的资料）

Mouse

E. coli Cell-free

N-10*His

P55850 (R136-R896)

13507

Full Length of Dsc3

RWAPIPCSMQENSLGPFPLFLQQVQSDAAQNYTVFYSISGRGADQEPLNWFFIERDTGNLYCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIKIEDENDNYPLFTEAIYAFEVPEGSRLGTVVGTVCATDKDEPDTMHTRLKYSILEQTPPSPGLFSVHPDTGVITTVSHYMDREVVDKYKLIMKVQDMNGQFFGLISTSTCIITVQDSNDNAPTFRQNTYETAVEENTYNVEILRIPVDDKDMINTANWKANFTILKGNENGWFKITTDPVTNEGVLCVVKPLDYEENRQVTLEIGVNNEAPFIKDVANRIPTMNRAMVTVHVKDQNEGPECKPPEQYVRIKENSAVGSKINGYKAYDPETKNSNGLRYKKLQDPKDWVSIEEVSGLLTISKTLDREIMAPRNDMYNITVMAIDQEGKSCTGTLAVNIEDVNDNAPEIIQDYIVICKPKMGYTDISAVDPDEPIHGPPFQFNLANTSPEVNRIWTLNQVNDTAARLSYQKTADVQIYNVPVTVKDRAGQSATKILRVNLCDCTHPSQCPLRSRSAGITLGKWAILAILLGIALLFSVLLTLVCGVVTARKGKHFPEDLAQQNLIISNTEAPGDDRVCSANGFTTHTANNSSQGFCGTMGSGMRNGGQETIEMMKGHQTLDSCRVAGHHHTLDSGRGGHMDTDNCRYTYSEWHSFTQPRLGEKLHVCNQNEDHIPSQDYVLTYNYEGRGSPAGSVGCCSEKQEEEGLDFLNNLEPKFLTLAETCTKR

Greater than 90% as determined by reducing SDS-PAGE.

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