FABP4 蛋白, Human (His)

FABP4 Protein, expressed mainly in adipocytes, crucially mediates lipid and retinoic acid transport. It binds long-chain fatty acids and retinoic acid, facilitating delivery to nuclear receptors. Functioning as a monomer and forming homodimers, FABP4 interacts with PPARG, contributing to its involvement in fatty acid metabolism and signaling pathways. FABP4 Protein, Human (His) is the recombinant human-derived FABP4 protein, expressed by E. coli , with N-6*His labeled tag. The total length of FABP4 Protein, Human (His) is 131 a.a., with molecular weight of ~15.0 kDa.

FABP4 是一种主要在脂肪细胞中表达的脂质转运蛋白，是脂质和视黄酸转运的关键介质。其作用包括与长链脂肪酸和视黄酸结合，促进它们递送至细胞核内各自的受体。FABP4 作为单体起作用并可以形成同型二聚体。此外，它还与 PPARG 相互作用，有助于其参与与脂肪酸代谢和信号通路相关的关键过程。

Human

E. coli

N-6*His

P15090 (C2-A132)

2167  [NCBI]

CDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKNTEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA

Approximately 15.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.