2. 重组蛋白
  3. CAR-T related Proteins Receptor Proteins Biotinylated Proteins
  4. Folate Receptor alpha (FR-alpha)
  5. FOLR1 蛋白, Human (Biotinylated, HEK293, His-Avi)

FOLR1 蛋白, Human (Biotinylated, HEK293, His-Avi)

目录号: HY-P72371
产品使用指南

FOLR1 蛋白是叶酸摄取的重要介质，与叶酸结合并促进 5-甲基四氢叶酸输送到细胞中。研究表明在中性 pH 值下具有高亲和力。FOLR1 蛋白, Human (Biotinylated, HEK293, His-Avi) 是重组的 FOLR1 蛋白，由 HEK293 表达，带有 C-Avi, C-6*His 标签。FOLR1 蛋白, Human (Biotinylated, HEK293, His-Avi) 全长 210 个氨基酸，分子量为 35-40 kDa。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
20 μg 询问价格 & 货期
100 μg 询问价格 & 货期

* Please select Quantity before adding items.

FOLR1 Protein, Human (Biotinylated, HEK293, His-Avi) 相关产品:

Top Publications Citing Use of Products

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The FOLR1 protein is an important mediator of folate uptake, binding to folate and promoting the delivery of 5-methyltetrahydrofolate into cells. Studies show high affinity at neutral pH. FOLR1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived FOLR1 protein, expressed by HEK293 , with C-Avi, C-6*His labeled tag. The total length of FOLR1 Protein, Human (Biotinylated, HEK293, His-Avi) is 210 a.a., with molecular weight of 35-40 kDa.
研究背景

FOLR1 蛋白作为叶酸摄取的关键介质，与叶酸和还原叶酸衍生物结合，促进 5-甲基四氢叶酸和叶酸类似物输送到细胞内部。各种研究证明，该过程的特点是在中性 pH 值下对叶酸和叶酸类似物具有高亲和力。值得注意的是，受体内吞作用后暴露于弱酸性 pH 值会引起构象变化，显着降低其对叶酸的亲和力，促进其释放。除了在叶酸转运中的作用之外，FOLR1 对于正常胚胎发育和适当的细胞增殖至关重要，强调了其在基本细胞过程中的重要性。
种属

Human
表达系统

HEK293
标签

C-Avi;C-6*His
蛋白编号

P15328 (R25-S234)
基因 ID
蛋白结构
N-term
FOLR1 (R25-S234)
Accession # P15328
6*His-Avi
C-term
同用名
Folate receptor alpha; FR-alpha; Adult folate-binding protein; FBP; Folate receptor 1; Folate receptor
氨基酸序列

RIAWARTELLNVCMNAKHHKEKPGPEDKLHEQCRPWRKNACCSTNTSQEAHKDVSYLYRFNWNHCGEMAPACKRHFIQDTCLYECSPNLGPWIQQVDQSWRKERVLNVPLCKEDCEQWWEDCRTSYTCKSNWHKGWNWTSGFNKCAVGAACQPFHFYFPTPTVLCNEIWTHSYKVSNYSRGSGRCIQMWFDPAQGNPNEEVARFYAAAMS

分子量

35-40 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

FOLR1 Protein, Human (Biotinylated, HEK293, His-Avi) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
FOLR1 Protein, Human (Biotinylated, HEK293, His-Avi)
目录号：
HY-P72371
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z