Glutathione S-transferase kappa 1/GSTK1 蛋白, Human (GST)

The GSTK1 protein acts as a glutathione S-transferase, promoting the binding of glutathione to exogenous and endogenous compounds, mainly through the model substrate 1-chloro-2,4-dinitrobenzene (CDNB). active activity. This enzymatic activity plays a vital role in the detoxification process, assisting in the binding of glutathione to various substrates. Glutathione S-transferase kappa 1/GSTK1 Protein, Human (GST) is the recombinant human-derived Glutathione S-transferase kappa 1/GSTK1 protein, expressed by E. coli , with N-GST labeled tag. The total length of Glutathione S-transferase kappa 1/GSTK1 Protein, Human (GST) is 225 a.a., with molecular weight of 52.4 kDa.

GSTK1（谷胱甘肽 S-转移酶 kappa 1）是一种属于谷胱甘肽 S-转移酶家族的酶，参与谷胱甘肽与外源和内源化合物缀合的催化。其显着的谷胱甘肽结合活性在模型底物 1-氯-2,4-二硝基苯 (CDNB) 中尤其显着。这种酶活性表明 GSTK1 在解毒过程中发挥作用，它促进谷胱甘肽与各种外源性和内源性化合物的结合，帮助它们从细胞中消除。所提供的信息基于参考通道，强调 GSTK1 的底物特异性及其在细胞解毒机制中的潜在重要性。进一步的研究可能会揭示有关 GSTK1 在细胞稳态和氧化应激保护中的生理意义的更多细节。

Human

E. coli

N-GST

Q9Y2Q3 (G2-L226)

373156  [NCBI]

GPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLPRKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRELWMRVWSRNEDITEPQSILAAAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGAFGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL

52.4 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.