GSTP1 蛋白, Human

Glutathione S-transferase P (GSTP1) is a member of GSTs family and plays an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 enables JUN kinase binding activity; glutathione transferase activity; and kinase regulator activity and is involved in negative regulation of cell population proliferation, intracellular signal transduction and macromolecule metabolic process as well. GSTP1 Protein, Human is the recombinant human-derived GSTP1 protein, expressed by E. coli , with tag free. The total length of GSTP1 Protein, Human is 210 a.a., with molecular weight of ~23.66 kDa.

谷胱甘肽S-转移酶P (GSTP1) 是 GSTs 家族的一员，GSTs 家族是一组通过催化许多疏水性和亲电性化合物与还原型谷胱甘肽结合而在解毒中发挥重要作用的酶。
GSTP1 增强 JUN 激酶的结合活性、谷胱甘肽转移酶活性、以及激酶调节活性。GSTP1 还参与细胞群体增殖、细胞内信号转导和大分子代谢过程的负调控。GSTP1 是含蛋白复合物的一部分，与多种疾病有关，包括脑部疾病 (多种)、癌症(多种)、血液肿瘤(多种)、生殖器官癌症(多种)及呼吸系统疾病(多种) ^[1][2][3]。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

E. coli

Tag Free

AAH10915.1 (M1-Q210)

2950  [NCBI]

MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYVSLIYTNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ

Approximately 23.66 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, 10% Glycerol, pH 8.0.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.